84877-63-4

Upstream product

• 173919-16-9 3-(4-bromophenyl)-4-(1-hydroxyethyl)sydnone 
• 26537-61-1 3-(4-bromophenyl)sydnone 
• 64-19-7 acetic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 84877-60-1 3-(4-bromophenyl)sydnone-4-N-methylcarboxamide 
• 352026-04-1 C₁₈H₁₂BrN₃O₅ 
• 352026-23-4 C₁₈H₁₀BrN₃O₄ 
• 173919-16-9 3-(4-bromophenyl)-4-(1-hydroxyethyl)sydnone 

Relevant academic research and scientific papers

Pyridine-catalyzed synthesis of quinoxalines as anticancer and anti-tubercular agents

Quinoxaline derivatized with coumarin viz., 3a–f and with sydnones viz., 7a–0 were synthesized using pyridine as catalyst. Among the coumarin derivatives, 3a and 3b have been screened for anticancer activity against 60 human cancer cell lines at NIH (USA)

Bismuth triflate-catalyzed friedel-crafts acylations of sydnones

Friedel-Crafts acylations of various 3-arylsydnones at the C4 position have been achieved in good yields using 4 equivalents of an alkyl anhydride and 25mol% each of bismuth triflate and lithium perchlorate in anhydrous acetonitrile at 95C. Acylations app

N-Bromosuccinimide (NBS) as Promoter for Acylation of Sydnones in the Presence of Acetic Anhydride under Neutral Conditions

Various 4 - acetyl sydnones (2) can be prepared by reaction of the corresponding 3-aryl sydnones (1) with acetic anhydride at ~110 °C promoted by N-Bromosuccinimide (NBS) as an effective reagent for acylation of sydnones under neutral conditions in satisf

1,3-Dibromo-5,5-dimethylhydantoin (DBH) as an efficient promoter for acetylation of 3-arylsydnones in the presence of acetic anhydride under neutral conditions

(Chemical Equation Presented) 1,3-Dibromo-5,5-dimethylhydantoin (DBH) has been found to efficiently promote the conversion of various 3-arylsydnones to their 4-acetyl congeners in the presence of acetic anhydride under neutral conditions in satisfactory y

Oxidation of 3-Aryl-4-(1-Hydroxyethyl)sydnones Using DMSO-Ac2O as Oxidant

Treatment of 3-aryl-4-(1-hydroxyethyl)sydnones with DMSO-Ac2O yielded esters and ketones, depending on the amount of Ac2O used; application of a limited amount of Ac2O with DMSO as an oxidant has been found to be the only method to convert the title compounds to the ketones.