848780-47-2

Upstream product

• 91229-97-9 (S)-2-[N-(tert-butoxycarbonyl)amino]-5-hydroxypentanoic acid benzyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 848780-45-0 Boc-(S)-N-Me-Tyr(TBS)-OH 
• 94732-15-7 (S)-2-(2-N-tert-butoxycarbonylamino)-3-[4-(tert-butyldimethylsilyloxy)phenyl]-propanoic acid 
• 112196-58-4 (S)-methyl-2-((tert-butoxycarbonyl)(methyl)amino)-3-(4-((tert-butyldimethyl-silyl)oxy)phenyl)propanoate 
• 100-39-0 benzyl bromide 
• 3978-80-1 Boc-Tyr-OH 
• 148529-07-1 (S)-5-Benzyloxy-2-tert-butoxycarbonylamino-pentanoic acid 
• 370867-49-5 Boc-(S)-Phe-(S)-N-Me-Tyr(TBS)-OMe 
• 370867-50-8 benzyl (S)-2-tert-butoxycarbonylamino-5-benzyloxypentanoate 
• 105589-11-5 2-tert-butoxycarbonylamino-5-ethoxycarbonyloxy-5-oxo-pentanoic acid benzyl ester 

Downstream Products

• 848780-60-9 C₇₂H₁₀₁N₆O₁₅PSi₂ 
• 370867-60-0 C₇₂H₁₀₁N₆O₁₅PSi₂ 
• 370867-59-7 phosphoric acid dibenzyl ester 2-benzyloxy-2-[9,15-dibenzyl-3-sec-butyl-6-[4-(tert-butyl-dimethyl-silanyloxy)-benzyl]-12-(3-hydroxy-propyl)-7,19-dimethyl-2,5,8,11,14,17-hexaoxo-1-oxa-4,7,10,13,16-pentaaza-cyclononadec-18-ylcarbamoyl]-ethyl ester 
• 370867-64-4 phosphoric acid dibenzyl ester 2-benzyloxy-2-[9,15-dibenzyl-3-sec-butyl-6-[4-(tert-butyl-dimethyl-silanyloxy)-benzyl]-7,19-dimethyl-2,5,8,11,14,17-hexaoxo-12-(3-oxo-propyl)-1-oxa-4,7,10,13,16-pentaaza-cyclononadec-18-ylcarbamoyl]-ethyl ester 
• 370867-52-0 Troc-(S)-Thr[Boc-(S)-Phs(Bn)-(S)-Phe-(S)-NMe-Tyr(TBS)-(S)-Ile]-(S)-Phe-OAllyl 
• 370867-66-6 phosphoric acid dibenzyl ester 2-benzyloxy-2-[2,15-dibenzyl-8-sec-butyl-21-hydroxy-5-(4-hydroxy-benzyl)-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-10-oxa-1,4,7,14,17-pentaaza-bicyclo[16.3.1]docos-12-ylcarbamoyl]-ethyl ester 
• 848780-48-3 Troc-(S)-Thr[Boc-(S)-Phs(Bn)-(S)-Phe-(S)-NMe-Tyr-(S)-Ile]-(S)-Phe-OAllyl 
• 370867-53-1 cyclo[Troc-(S)-Thr-(S)-Phe-(S)-Phs(Bn)-(S)-Phe-(S)-N-Me-Tyr(TBS)-(S)-Ile] 
• 848780-52-9 cyclo[Boc-(S)-Thr-(S)-Phe-(S)-Phs(Bn)-(S)-Phe-(S)-N-Me-Tyr(TBS)-(S)-Ile] 
• 370867-58-6 cyclo[Boc-(S)-Thr-(S)-Phe-(S)-Phs-(S)-Phe-(S)-N-Me-Tyr(TBS)-(S)-Ile] 

Relevant academic research and scientific papers

Synthetic studies of the cyclic depsipeptides bearing the 3-amino-6-hydroxy-2-piperidone (Ahp) unit. Total synthesis of the proposed structure of micropeptin T-20

The first total synthesis of a cyclic depsipeptide possessing the 3-amino-6-hydroxy-2-piperidone (Ahp) unit was successfully achieved in a convergent manner by the oxidative construction of the Ahp unit at the later stage of the synthesis. This synthetic work provides data indicating that the structure of the target Ahp-depsipeptide, micropeptin T-20, should be re-examined.