848821-62-5Relevant academic research and scientific papers
Enantioselective organocatalyzed α sulfenylation of aldehydes
Marigo, Mauro,Wabnitz, Tobias C.,Fielenbach, Doris,Jorgensen, Karl Anker
, p. 794 - 797 (2007/10/03)
The facile elaboration of optically active α-sulfanyl-substituted aldehydes makes their direct preparation from unmodified aldehydes and 1-benzylsulfanyl-1,2,4-triazole particularly valuable. The substituted aldehydes are formed with excellent enantiosele
A general organocatalyst for direct α-functionalization of aldehydes: Stereoselective C-C, C-N, C-F, C-Br, and C-S bond-forming reactions. Scope and mechanistic insights
Franzen, Johan,Marigo, Mauro,Fielenbach, Doris,Wabnitz, Tobias C.,Kjaersgaard, Anne,Jorgensen, Karl Anker
, p. 18296 - 18304 (2007/10/03)
The development of a general organocatalyst for the α- functionalization of aldehydes, via an enamine intermediate, is presented. Based on optically active α,α-diarylprolinol silyl ethers, the scope and applications of this catalyst for the stereogenic fo
