84888-71-1

Usage

Uses

Used in Pharmaceutical Industry:
5-[(Benzylsulfanyl)methyl]-5-methyl-2,4-imidazolidinedione is used as a pharmaceutical intermediate for the synthesis of other compounds, leveraging its unique structure and properties to create new therapeutic agents.
Used in Medicine:
5-[(Benzylsulfanyl)methyl]-5-methyl-2,4-imidazolidinedione is used as an anticonvulsant and anti-inflammatory agent due to its biological activity, offering potential benefits in the treatment of various conditions.
Used in Antimicrobial Applications:
5-[(Benzylsulfanyl)methyl]-5-methyl-2,4-imidazolidinedione is used as an antimicrobial agent, demonstrating effectiveness against certain types of bacteria, which could be valuable in the development of new antibiotics.
Used in Antifungal Applications:
5-[(Benzylsulfanyl)methyl]-5-methyl-2,4-imidazolidinedione is used as an antifungal agent, showing promise in combating fungal infections, which could contribute to the development of novel antifungal medications.
Further research is necessary to fully understand the pharmacological properties and potential applications of 5-[(Benzylsulfanyl)methyl]-5-methyl-2,4-imidazolidinedione in medicine and related fields.

Upstream product

• 10230-69-0 benzylthioacetone 
• 506-87-6 ammonium carbonate 
• 100-53-8 phenylmethanethiol 
• 33109-56-7 5-chloromethyl-5-methylhydantoin 
• 151-50-8 potassium cyanide 

Downstream Products

• 950672-42-1 (5S)-5-benzylsulfanylmethyl-5-methyl-imidazolidine-2,4-dione (1S)-α-methylbenzylamine salt 
• 1206882-37-2 (R,S)-5-methyl-5-phenylmethanesulfinylmethyl-imidazolidine-2,4-dione 
• 52616-59-8 (S)-2-amino-3-benzylsulfanyl-2-methyl-propionic acid 
• 459818-48-5 (5S)-5-methyl-5-{[(phenylmethyl)thio]methyl}imidazolidine-2,4-dione 
• 459818-49-6 (R)-5-(benzylthiomethyl)-5-methylimidazolidine-2,4-dione 
• 674348-00-6 [4-methyl-2,5-dioxoimidazolidin-4-yl]methanesulphonyl chloride 

Relevant academic research and scientific papers

NOVEL CRYSTAL MODIFICATIONS

Novel crystal modifications of (5S)-5-[4-(5-chloro-pyridin-2-yloxy)-piperidine-1-sulfonylmethyl]-5-methyl-imidazolidine-2,4-dione are disclosed together with processes for preparing such modifications, pharmaceutical compositions comprising such a modification, and the use of such a modification in therapy.

PROCESS FOR PRODUCING L-a-METHYLCYSTEINE DERIVATIVE

A process for easily producing an L-α-methylcysteine derivative or its salt, which is useful as a drug intermediate, from a cheap easily procurable raw material through an enzymatic D-stereoselective hydrolysis of racemic 5-halomethyl-5-methyl-hydantoin. L-α-methylcysteine derivative or its salt is produced by converting racemic 5-halomethyl-5-methylhydantoin to L-5-halomethyl-5-methylhydantoin through an enzymatic D-stereoselective hydrolysis, reacting the L-5-halomethyl-5-methylhydantoin with a sulfurizing agent into L-5-methyl-5-thiomethylhydantoin and hydrolyzing the L-5-methyl-5-thiomethylhydantoin.

1-SULPHONYL PIPERIDINE DERIVATIVES

Piperidine derivatives of formula (1) that are useful in the inhibition of metalloproteinases, in particular TNF-α Converting Enzyme (TACE) and thus in the treatment of autoimmune disease, allergic/atopic diseases, transplant rejection, graft versus host disease, cardiovascular disease, reperfusion injury and malignancy.

IMIDAZOLIDINEDIONE-DERIVATIVES AND THEIR USE AS METALLOPROTEINASE INHIBITORS

The invention provides compounds of formula in which R1, G1 and G2 have the meanings defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.

SULPHONAMIDE DERIVATIVES AND THEIR USE AS TACE INHIBITORS

Sulphonamide derivatives that are useful in the inhibition of metalloproteinases and in particular in the inhibition of TNF-α Converting Enzyme (TACE).