848909-01-3Relevant academic research and scientific papers
Nucleophilic opening of epoxyazepanes: Expanding the family of polyhydroxyazepane-based glycosidase inhibitors
Li, Hongqing,Schuetz, Catherine,Favre, Sylvain,Zhang, Yongmin,Vogel, Pierre,Sinay, Pierre,Bleriot, Yves
, p. 1653 - 1662 (2006)
A range of new tetra- and pentahydroxylated seven-membered iminoalditols has been efficiently synthesized from epoxyazepane precursors via nucleophilic opening with hydride or oxygenated species and subsequent hydrogenolysis. One tetrahydroxylated azepane
New 1-amino-1-deoxy- and 2-amino-2-deoxy-polyhydroxyazepanes: Synthesis and inhibition of glycosidases
Li, Hongqing,Bleriot, Yves,Mallet, Jean-Maurice,Rodriguez-Garcia, Eliazar,Vogel, Pierre,Zhang, Yongmin,Sinay, Pierre
, p. 313 - 319 (2007/10/03)
Eight new seven-membered ring iminoalditols, displaying an amino group and a hydroxymethyl group on the ring, have been synthesized from d-arabinose via epoxidation of a protected azacycloheptene and subsequent nucleophilic opening. Three of them show a p
