Nucleophilic opening of epoxyazepanes: Expanding the family of polyhydroxyazepane-based glycosidase inhibitors

DOI: 10.1039/b518117h

Source and publish data:

Organic and Biomolecular Chemistry p. 1653 - 1662 (2006)

Update date:2022-08-03

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Authors:

Li, Hongqing

Schuetz, Catherine

Favre, Sylvain

Zhang, Yongmin

Vogel, Pierre

Sinay, Pierre

Bleriot, Yves

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Article abstract of DOI:10.1039/b518117h

A range of new tetra- and pentahydroxylated seven-membered iminoalditols has been efficiently synthesized from epoxyazepane precursors via nucleophilic opening with hydride or oxygenated species and subsequent hydrogenolysis. One tetrahydroxylated azepane

Full text of DOI:10.1039/b518117h

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