84891-23-6

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 586-95-8 pyridine-4-methanol 
• 83031-02-1 t-butoxycarbonyl-L-phenylalanine 4-picolyl ester 

Downstream Products

• 85974-15-8 t-butoxycarbonyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 85974-24-9 t-butoxycarbonyl-O-benzyl-L-seryl-ε-benzyloxycarbonyl-L-lysyl-L-histidyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 85974-16-9 t-butoxycarbonyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 85974-17-0 t-butoxycarbonyl-β-benzyl-L-aspartyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 85974-21-6 N,N^Im-di-t-butoxycarbonyl-L-histidyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 85974-22-7 t-butoxycarbonyl-ε-benzyloxycarbonyl-L-lysyl-L-histidyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 85974-18-1 t-butoxycarbonyl-ε-benzyloxycarbonyl-L-lysyl-β-benzyl-L-aspartyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 83030-60-8 N^α-t-butoxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanine 
• 83030-92-6 N^α-benzyloxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanine 
• 83030-59-5 N^α-t-butoxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanylhydrazide 
• 83030-58-4 Boc-Arg(NO₂)-Pro-Pro-Gly-Phe-Ser(Bzl)-Pro-Phe-OPic 
• 83030-91-5 N^α-benzyloxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanine 4-picolyl ester 
• 47507-91-5 (S)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionic acid pyridin-4-ylmethyl ester 
• 83030-97-1 Boc-Ser(Bzl)-Pro-Phe-OPic 

Relevant academic research and scientific papers

Amino-acids and Peptides Part 47. Synthesis of Peptides Related to Bovine Prothrombin.

It is known that Fragment 2 of bovine prothrombin inhibits the coagulation of blood plasma, and various considerations suggest that the inhibitory site might be in the 198-215 region (1) of prothrombin.Peptides related to the sequences in the 202-215 region of bovine prothrombin (2) have been synthesised by the picolyl ester method for examination as possible anticoagulation agents, including the bovine fragment 202-215 and the human fragment 204-215, variants of the sequence 210-215, and the bovine and human sequences 202-209.

Amino-acids and Peptides. Part 46. Synthesis of Bradykinin Analogues Modified in the Vicinity of the Carboxy-group

In order to investigate further the effect on biological activity of structural changes in the vicinity of the terminal carboxy-group, the following analogues of bradykinin have been synthesised by the picolyl ester method: bradykinyl-L-isoleucine (2), -L