84892-42-2

Usage

Uses

Used in Organic Synthesis:
TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL is used as a key intermediate in the synthesis of various organic compounds due to its unique structural features and reactivity.
Used in Pharmaceutical Research:
In the pharmaceutical industry, TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL is utilized as a starting material for the development of new drugs, leveraging its potential biological activities and pharmacological properties.
Used in Production of Chemical Intermediates:
TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL serves as a precursor in the manufacturing process of various chemical intermediates, contributing to the synthesis of a wide range of chemical products.
Used in Drug Development:
TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL is employed as a building block in the creation of novel pharmaceuticals, capitalizing on its potential therapeutic applications and the ability to be modified for specific medicinal purposes.

Upstream product

• 4894-75-1 1-phenyl-4-cyclohexanone 
• 5437-46-7 trans-4-phenylcyclohexanol 

Relevant academic research and scientific papers

PNO ligand containing planar chiral ferrocene and axial chiral diphenol and application thereof

The invention discloses a PNO ligand containing planar chiral ferrocene and axially chiral diphenol and application of the PNO ligand. The PNO ligand containing planar chiral ferrocene and axially chiral diphenol is shown in any one of general formulas (I)-(IV). Or a PNO ligand containing planar chiral ferrocene and axial chiral diphenol as shown in any one of general formulas (V)-(VIII); compared with a previously reported tridentate ligand, the PNO ligand containing the planar chiral ferrocene and the axial chiral diphenol not only has good stability and easiness in synthesis, but also has planar chirality and axial chirality and has a good chiral environment, so that not only is excellent selectivity to a substrate ensured, but also the catalytic activity of a catalyst and the application range of the substrate are further improved. The chiral raw materials used in the invention are commercial bulk products, and the ligand synthesis route is simpler, so that large-scale production can be well carried out, and the method has a huge commercial application prospect.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

AZABENZIMIDAZOLE DERIVATIVES

The present invention relates to compounds of general formula (I), wherein the group R1, R2, X, Y and z are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the AMP-activated protein kinase (AMPK) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.

NEW AZABENZIMIDAZOLE DERIVATIVES

The present invention relates to compounds of general formula I, wherein the group R1, R2, X, Y and z are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the AMP-activated protein kinase (AMPK) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.