848927-66-2Relevant academic research and scientific papers
A convergent enantioselective synthesis of the anti-malarial agent (+)-febrifugine
Ashoorzadeh, Amir,Caprio, Vittorio
, p. 346 - 348 (2005)
Chiral pool derived 3-benzyloxy-3,4,5,6-tetrahydropyridine N-oxide underwent regio- and diastereoselective 1,3-dipolar cycloaddition with N-allylquinazolone to give a cycloadduct that was elaborated to (+)-febrifugine a potent anti-malarial alkaloid.
