848927-68-4Relevant articles and documents
Synthesis of (S)-3-hydroxytetrahydropyran from L-glutamic acid
Geng, Yang,Zheng, Maolin,Li, Jingya,Zou, Dapeng,Wu, Yusheng,Wu, Yangjie
, p. 3966 - 3969 (2017/09/26)
A concise synthesis of (S)-3-hydroxytetrahydropyran from natural L-glutamic acid has been developed. The intramolecular etherification starting from 1,5-diol was promoted by trifluoromethanesulfonic anhydride. The clinnamates of the alcohols were prepared
3-benzyloxy-tetrahydropyrane, preparation method thereof and preparation method of single-configured tetrahydropyrane-3-cyclitol
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, (2017/10/27)
The invention relates to 3-benzyloxy-tetrahydropyrane, a preparation method thereof and a preparation method of single-configured tetrahydropyrane-3-cyclitol, and belongs to the technical field of medicines. The 3-benzyloxy-tetrahydropyrane has a structur
Synthetic evaluation of an enantiopure tetrahydropyridine N-oxide. Synthesis of (+)-febrifugine
Ashoorzadeh, Amir,Archibald, Glenn,Caprio, Vittorio
experimental part, p. 4671 - 4680 (2009/10/09)
A study into the synthesis and synthetic utility of (S)-3-benzyloxy-3,4,5,6-tetrahydropyridine N-oxide is described. This nitrone is readily accessed from l-glutamic acid and the regio- and stereoselectivity of cycloaddition of this compound with a range
A convergent enantioselective synthesis of the anti-malarial agent (+)-febrifugine
Ashoorzadeh, Amir,Caprio, Vittorio
, p. 346 - 348 (2007/10/03)
Chiral pool derived 3-benzyloxy-3,4,5,6-tetrahydropyridine N-oxide underwent regio- and diastereoselective 1,3-dipolar cycloaddition with N-allylquinazolone to give a cycloadduct that was elaborated to (+)-febrifugine a potent anti-malarial alkaloid.
