848945-98-2Relevant academic research and scientific papers
Remote stereocontrol by sulfinyl groups: Reduction of δ- ketosulfoxides
Garcia Ruano, Jose L.,Fernandez-Ibanez, M. Angeles,Maestro, M. Carmen,Rodriguez-Fernandez, M. Mercedes
, p. 1796 - 1801 (2005)
(Chemical Equation Presented) The reduction of δ-ketosulfoxides constitutes the first evidence of the efficiency of the sulfinyl group to control the stereoselectivity of 1,5-asymmetric induction processes. The use of DIBAL/Yb(OTf)3 or L-Selectride as the reducing agents provides δ-hydroxysulfoxides with the opposite configuration at the hydroxylic carbon in a highly stereoselective way.
