849100-08-9

Upstream product

• 849100-05-6 2-(3,4-dimethoxy-phenyl)-4-methoxy-3-oxo-butyric acid methyl ester 
• 75-77-4 chloro-trimethyl-silane 
• 15964-79-1 methyl (3,4-dimethoxyphenyl)acetate 

Downstream Products

• 849100-10-3 1,2-Dimethoxy-4-{(E)-3-methoxy-1-[1-methoxy-1-trimethylsilanyloxy-meth-(E)-ylidene]-2-trimethylsilanyloxy-allyl}-benzene 
• 849100-12-5 (3,4-dimethoxy-phenyl)-(4-hydroxy-3-methoxy-5-oxo-5H-furan-2-ylidene)-acetic acid methyl ester 
• 849100-14-7 (3,4-dimethoxy-phenyl)-(3-methoxy-5-oxo-4-trifluoromethanesulfonyloxy-5H-furan-2-ylidene)-acetic acid methyl ester 
• 20988-32-3 per-O-methylvariegatic acid 
• 20988-30-1 variegatic acid 

Relevant academic research and scientific papers

Synthesis of natural pulvinic acids based on a '[3+2] cyclization-Suzuki cross-coupling' strategy

A number of pulvinic acid natural products were prepared based on Suzuki cross coupling reactions of α-hydroxy-γ-alkylidenebutenolides which are readily available by cyclization of 1,3-bis-silyl enol ethers with oxalyl chloride. The formal total synthesis