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(S)-tert-butyl 3-(isopropylamino)pyrrolidine-1-carboxylate, also known as (S)-t-Boc-Ile-OH, is a chemical compound that serves as a versatile building block in organic synthesis and pharmaceutical research. It is a derivative of the amino acid isoleucine, characterized by the presence of a tert-butyl and isopropyl groups, which provide steric hindrance and contribute to the control of stereochemistry in chemical reactions. The pyrrolidine ring in its structure offers stability and rigidity, making it a valuable component in the design of bioactive molecules. (S)-tert-butyl 3-(isopropylamino)pyrrolidine-1-carboxylate has a broad spectrum of applications in medicinal chemistry and drug discovery.

849107-00-2

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849107-00-2 Usage

Uses

Used in Pharmaceutical Research:
(S)-tert-butyl 3-(isopropylamino)pyrrolidine-1-carboxylate is used as a building block in the synthesis of peptides and proteins for pharmaceutical research. Its steric hindrance and structural stability make it an important component in the development of bioactive molecules with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-tert-butyl 3-(isopropylamino)pyrrolidine-1-carboxylate is used as a key intermediate for the preparation of various complex organic compounds. Its unique structural features facilitate the synthesis of target molecules with specific properties and functions.
Used in Medicinal Chemistry:
(S)-tert-butyl 3-(isopropylamino)pyrrolidine-1-carboxylate is employed as a structural element in the design of novel bioactive molecules for medicinal chemistry. Its ability to control stereochemistry and provide stability makes it a valuable tool in the development of new drugs with improved efficacy and selectivity.
Used in Drug Discovery:
In drug discovery, (S)-tert-butyl 3-(isopropylamino)pyrrolidine-1-carboxylate is utilized as a starting material for the development of new pharmaceutical agents. Its versatility and structural features enable the exploration of diverse chemical space and the identification of potential drug candidates with novel mechanisms of action.
Used in Stereochemistry Control:
(S)-tert-butyl 3-(isopropylamino)pyrrolidine-1-carboxylate is used as a chiral auxiliary in controlling the stereochemistry of chemical reactions. Its presence helps to dictate the spatial arrangement of atoms in the synthesis of enantiomerically pure compounds, which is crucial for the development of chiral drugs with desired biological activities.
Used in Bioactive Molecule Design:
In the design of bioactive molecules, (S)-tert-butyl 3-(isopropylamino)pyrrolidine-1-carboxylate is used as a structural motif to impart stability and rigidity. Its incorporation into molecular frameworks can enhance the binding affinity and selectivity of drug candidates, leading to improved therapeutic outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 849107-00-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,1,0 and 7 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 849107-00:
(8*8)+(7*4)+(6*9)+(5*1)+(4*0)+(3*7)+(2*0)+(1*0)=172
172 % 10 = 2
So 849107-00-2 is a valid CAS Registry Number.

849107-00-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl (3S)-3-(propan-2-ylamino)pyrrolidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names (S)-1-N-Boc-3-(Isopropylamino)pyrrolidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:849107-00-2 SDS

849107-00-2Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS

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Paragraph 00241, (2015/10/05)

Provided herein are compounds of formula I and compositions containing the compounds. The compounds and compositions are useful in the methods of inhibiting the action of ERK5, a BET family protein or both. In certain embodiments, the compounds and compositions are useful in the prevention, amelioration or treatment of a ERK5-mediated disease, a BET protein-mediated disease or both

AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS

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Page/Page column 31, (2010/06/16)

The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment

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