849109-71-3

Upstream product

• 301548-32-3 t-butyl (7-hydroxynaphthalen-1-yl)carbamate 
• 118-46-7 8-amino-2-naphthol 
• 1443320-60-2 (7-benzyloxy-naphthalen-1-yl)-carbamic acid tert-butyl ester 
• 330213-81-5 7-(benzyloxy)-1-naphthalenamine 
• 29921-51-5 1-iodo-7-hydroxynaphthalene 
• 100-39-0 benzyl bromide 

Downstream Products

• 849109-72-4 7-benzyloxy-naphthalene-1-carbaldehyde 
• 849109-74-6 1-(7-benzyloxy-naphthalen-1-yl)-2-pyridin-4-yl-ethane-1,2-dione 
• 849109-76-8 8-(2-phenyl-5-pyridin-4-yl-3H-imidazol-4-yl)-naphthalen-2-ol 
• 849109-75-7 4-[5-(7-benzyloxy-naphthalen-1-yl)-2-phenyl-1H-imidazol-4-yl]-pyridine 
• 849109-51-9 phenyl-carbamic acid 8-(2-phenyl-5-pyridin-4-yl-3H-imidazol-4-yl)-naphthalen-2-yl ester 
• 1139877-13-6 7-Benzyloxy-1-naphthoic Acid 

Relevant academic research and scientific papers

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly di

INHIBITORS OF PRENYL-PROTEIN TRANSFERASE

The present invention is directed to peptidomimetic piperazine-containing macrocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras