849112-88-5

Upstream product

• 849112-85-2 (4S,5R,6S)-4,6-Bis-(tert-butyl-dimethyl-silanyloxy)-1-thia-spiro[4.4]non-2-ene 
• 5707-04-0 Phenylselenyl chloride 
• 7288-28-0 2,4-bis(trimethylsiloxy)-5-methylpyrimidine 
• 849112-83-0 (4S,5R,6S)-1-Thia-spiro[4.4]non-2-ene-4,6-diol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 630059-93-7 (3R,5S,6S)-3-Phenyl-1,4-dioxa-7-thia-dispiro[4.0.4.3]tridec-9-en-2-one 
• 849112-78-3 C₁₉H₂₂O₅S 
• 849112-77-2 (3R,5S,6S,9R,10S)-9,10-Dihydroxy-3-phenyl-1,4-dioxa-7-thia-dispiro[4.0.4.3]tridecan-2-one 
• 849112-79-4 C₁₁H₁₈O₃S 

Relevant academic research and scientific papers

Stereoselective synthesis of conformationally constrained 2′-deoxy-4′-thia β-anomeric spirocyclic nucleosides featuring either hydroxyl configuration at C5′

(Chemical Equation Presented) An enantioselective approach to 2′-deoxy-4′-thia spirocyclic nucleosides featuring an α- or β-hydroxyl substituent at C-5′ of the carbocyclic ring is detailed. The starting point is the mandelate acetal 8. The overall strateg

Spirocyclic restriction of nucleosides

The concept of spirocyclic restriction as applied broadly to the field of nucleoside mimics makes possible the generation of diastereomeric pairs configured with a syn- or anti-oriented hydroxyl substituent at C5′. The development of concise synthetic rou