849145-46-6

Basic information

• Product Name: N-[N-(3,5-difluorophenylacetyl)-(S)-alanyl]-N-[4-(4-nitrophenyl)]thiazol-2-ylamine
• Synonyms: N-[N-(3,5-difluorophenylacetyl)-(S)-alanyl]-N-[4-(4-nitrophenyl)]thiazol-2-ylamine
• CAS NO: 849145-46-6
• Molecular Weight: 446.434
• Mol File: 849145-46-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[N-(3,5-difluorophenylacetyl)-(S)-alanyl]-N-[4-(4-nitrophenyl)]thiazol-2-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[N-(3,5-difluorophenylacetyl)-(S)-alanyl]-N-[4-(4-nitrophenyl)]thiazol-2-ylamine(849145-46-6)
• EPA Substance Registry System: N-[N-(3,5-difluorophenylacetyl)-(S)-alanyl]-N-[4-(4-nitrophenyl)]thiazol-2-ylamine(849145-46-6)

Safety Data

• Hazardous Substances Data: 849145-46-6(Hazardous Substances Data)

Upstream product

• 105184-38-1 3,5-difluorophenyl acetic acid 

Downstream Products

• 849145-47-7 N-[4-(4-amino-phenyl)-thiazol-2-yl]-2-[2-(3,5-difluoro-phenyl)-acetylamino]-propionamide 
• 849145-48-8 N-[N-(3,5-difluorophenylacetyl)-(S)-alanyl]-N-{4-[4-(N-pyridyl-3-carbonyl)aminophenyl]}thiazol-2-ylamine 

Relevant articles and documents

Substituted thiazolamide coupled to a redox delivery system: A new γ-secretase inhibitor with enhanced pharmacokinetic profile

Inhibition of γ-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce pathogenic Aβ peptides, is an attractive approach for the treatment of Alzheimer's disease. We have designed a new γ-secretase thi