84922-66-7

Upstream product

• 82310-54-1 (2R,3R,11bS)-(-)-10-benzyloxy-3-ethyl-1,3,4,6,7,11b-hexahydro-9-methoxy-2H-benzoquinolizine-2-acetic acid ethyl ester 
• 73053-58-4 (+/-)-10-benzyloxy-3α-ethyl-1,3,4,6,7,11bα-hexahydro-9-methoxy-2H-benzoquinolizine-2β-acetic acid ethyl ester 

Relevant academic research and scientific papers

Quinolizidines. XX. Racemic and Chiral Syntheses of the Alangium Alkaloids 9-Demethylprotoemetinol and 10-Demethylprotoemetinol

The synthesis of (+/-)-9-demethylprotoemetinol was accomplished by LiAlH4 reduction of the tricyclic ester (+/-)-5 and subsequent debenzylation of the resulting tricyclic alchol (+/-)-10.Acetylation of (+/-)-3d with acetic anhydride and pyridin

SYNTHESES OF (-)-9-DEMETHYLPROTOEMETINOL AND (+/-)- AND (-)-10-DEMETHYLPROTOEMETINOLS

The synthesis of (-)-9-demethylprotoemetinol (X) was achieved by LiAlH4 reduction of the (-)-tricyclic ester XIV followed by catalytic hydrogenolysis of the resulting (-)-tricyclic alcohol XI.Acetylation of (-)-X yielded the (-)-diacetate XVII.Parallel sy