849240-74-0

Upstream product

• 660853-04-3 N-benzyloxycarbonyl-D-alanyl-D-serine methyl ester 
• 14470-28-1 mono-4-methoxytrityl chloride 
• 26607-51-2 N-benzyloxycarbonyl-D-alanine 

Downstream Products

• 849240-79-5 {(R)-1-[(S)-1-[Benzyloxy-((S)-2,3-bis-benzyloxy-propoxy)-phosphoryloxymethyl]-2-(tert-butyl-diphenyl-silanyloxy)-ethylcarbamoyl]-ethyl}-carbamic acid benzyl ester 
• 849240-78-4 {(R)-1-[(S)-1-(Benzyloxy-diisopropylamino-phosphanyloxymethyl)-2-(tert-butyl-diphenyl-silanyloxy)-ethylcarbamoyl]-ethyl}-carbamic acid benzyl ester 
• 849240-80-8 ((R)-1-{(S)-2-[Benzyloxy-((S)-2,3-bis-benzyloxy-propoxy)-phosphoryloxy]-1-hydroxymethyl-ethylcarbamoyl}-ethyl)-carbamic acid benzyl ester 
• 849240-77-3 {(R)-1-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-hydroxymethyl-ethylcarbamoyl]-ethyl}-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis of structural variants of Staphylococcus aureus lipoteichoic acid (LTA)

Based on 1,2-O-isopropylidene-sn-glycerol, which is readily available from d-mannitol, five chiral building blocks for the construction of structural variants of Staphylococcus aureus LTA designed and synthesized. Ligation of these building blocks led readily to the target molecules 1 and 2. They demonstrated that the d-alanine residues at the glycerophosphate backbone are decisive for the activation of the immune system.