849242-02-0Relevant articles and documents
Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists
Cappellacci, Loredana,Franchetti, Palmarisa,Pasqualini, Michela,Petrelli, Riccardo,Vita, Patrizia,Lavecchia, Antonio,Novellino, Ettore,Costa, Barbara,Martini, Claudia,Klotz, Karl-Norbert,Grifantini, Mario
, p. 1550 - 1562 (2007/10/03)
A number of 3′-C-methyl analogues of selective adenosine receptor agonists such as CPA, CHA, CCPA, 2′-Me-CCPA, NECA, and IB-MECA was synthesized to further investigate the subdomain of the receptor that binds the ribose moiety of the ligands. Affinity dat