205171-10-4 Usage
General Description
2,6-Dichloro-9-(2-C-methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine is a compound that is a derivative of purine, a nitrogenous base found in DNA and RNA. 2,6-Dichloro-9-(2-C-Methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine is a nucleoside analog, meaning it is similar in structure to the building blocks of DNA and RNA. It contains two chlorine atoms and a methyl group, as well as three benzoyl groups attached to the ribofuranosyl moiety. These chemical modifications give it unique properties and potentially different biological activities compared to the natural purines found in cells. 2,6-Dichloro-9-(2-C-Methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine may be of interest for its potential use in drug development or research related to nucleic acids and their functions.
Check Digit Verification of cas no
The CAS Registry Mumber 205171-10-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,1,7 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 205171-10:
(8*2)+(7*0)+(6*5)+(5*1)+(4*7)+(3*1)+(2*1)+(1*0)=84
84 % 10 = 4
So 205171-10-4 is a valid CAS Registry Number.
205171-10-4Relevant articles and documents
INHIBITORS OF ADENOSINE 5'-NUCLEOTIDASE
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Paragraph 0266, (2018/04/21)
Compounds that modulate the conversion of AMP to adenosine by 5'- nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment
Synthesis and Evaluation of 2,6-Modified Purine 2′-C-Methyl Ribonucleosides as Inhibitors of HCV Replication
Zhou, Longhu,Zhang, Hongwang,Tao, Sijia,Ehteshami, Maryam,Cho, Jong Hyun,McBrayer, Tamara R.,Tharnish, Philip,Whitaker, Tony,Amblard, Franck,Coats, Steven J.,Schinazi, Raymond F.
, p. 17 - 22 (2016/02/03)
A variety of 2,6-modified purine 2′-C-methylribonucleosides and their phosphoramidate prodrugs were synthesized and evaluated for inhibition of HCV RNA replication in Huh-7 cells and for cytotoxicity in various cell lines. Cellular pharmacology and HCV polymerase incorporation studies on the most potent and selective compound are reported.