84927-67-3

Upstream product

• 67-97-0 vitamin D₃ 
• 84927-66-2 7,8-dihydroxy-7,8-dihydrovitamin D₃ 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 33813-99-9 Grundmann's alcohol 
• 96685-53-9 (2Z)-2-<(5S)-5-(tert-butyldimethylsilyloxy)-2-methylene-cyclohexylidene>-ethanol 
• 84927-73-1 tert-Butyl-dimethyl-{(S)-4-methylene-3-[2-[(1R,3aS,7aR)-7a-methyl-1-[(S)-1-methyl-2-(2-methyl-allyloxy)-ethyl]-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-cyclohexyloxy}-silane 
• 84927-72-0 23-oxa-25,26-dehydrovitamin D₃ 
• 84927-61-7 23-oxa-25-hydroxyvitamin D₃ 
• 100858-27-3 (S)-(Z)-{2-[5-(tert-butyldimethylsiloxy)-2-methylenecyclohexylidene]ethyl}diphenylphosphine oxide 
• 138313-18-5 <(1Z),(5S)>-2-<5-(t-butyldimethylsilyl)oxy-2-methylenecyclohexylidene>-1-chloroethane 

Relevant academic research and scientific papers

Studies on a Convergent Route to Side-Chain Analogues of Vitamin D: 25-Hydroxy-23-oxavitamin D3

Permanganate oxidation of vitamin D3 affords the 7,8-diol 4a, which was successively silylated to 4b and then oxidatively cleaved and reduced to afford 3c.The latter was converted in several steps to phosphine oxide 3b, a useful A-ring fragment for analog