849338-78-9Relevant articles and documents
Facile Synthesis of Kwakhurin, a Marker Compound of Pueraria mirifica and Its Quantitative NMR Analysis for Standardization as a Reagent
Tsuji, Genichiro,Yusa, Masaaki,Masada, Sayaka,Yokoo, Hidetomo,Hosoe, Junko,Hakamatsuka, Takashi,Demizu, Yosuke,Uchiyama, Nahoko
, p. 797 - 801 (2020/09/18)
The side effects of kwao keur dietary supplements (obtained from the tuberous root of Pueraria mirifica) have recently been reported by the Ministry of Health, Labour and Welfare, Japan. To control the quality of kwao keur products, its ingredients need t
The first total synthesis of kwakhurin, a characteristic component of a rejuvenating plant, "kwao keur": Toward an efficient synthetic route to phytoestrogenic isoflavones
Ito, Fumihiro,Iwasaki, Misako,Watanabe, Toshiko,Ishikawa, Tsutomu,Higuchi, Yoshihiro
, p. 674 - 681 (2007/10/03)
A convergent synthesis of kwakhurin (5), a characteristic estrogen-like isoflavone of Pueraria mirifica (Leguminosae), is described. Isoflavone skeleton 31 was constructed by Suzuki-Miyaura coupling of 3-bromochromone 26 (AC-ring) and arylboronic acid 30