849361-83-7Relevant academic research and scientific papers
LAULIMALIDE ANALOGS AND USES THEREOF
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Page/Page column 144, (2010/02/11)
The present invention provides compounds having formula 1: (I) and pharmaceutically acceptable derivatives thereof, wherein R1-R10, q, t, X0, X1, A, B, D, E, G, J, K, L, M and Z are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of disorders associated with cellular hyperproliferation.
Stereoselective synthesis of syn- and anti-1,3- and 1,2-dimethyl arrays via asymmetric conjugate additions
Williams, David R,Kissel, William S,Li, Jie Jack,Mullins, Richard J
, p. 3723 - 3727 (2007/10/03)
Asymmetric conjugate additions have been investigated with enantiopure N-enoyloxazolidinones for efficient construction of syn and anti-1,3-dimethyl arrays on an acyclic carbon backbone. Reactions of Yamamoto organocopper species exhibit characteristics of double asymmetric induction resulting from influences of the 4-substituted chiral auxiliary and features of side chain stereochemistry.
