459168-11-7Relevant academic research and scientific papers
Stereoselective synthesis of syn- and anti-1,3- and 1,2-dimethyl arrays via asymmetric conjugate additions
Williams, David R,Kissel, William S,Li, Jie Jack,Mullins, Richard J
, p. 3723 - 3727 (2002)
Asymmetric conjugate additions have been investigated with enantiopure N-enoyloxazolidinones for efficient construction of syn and anti-1,3-dimethyl arrays on an acyclic carbon backbone. Reactions of Yamamoto organocopper species exhibit characteristics of double asymmetric induction resulting from influences of the 4-substituted chiral auxiliary and features of side chain stereochemistry.
Diastereoselection in the conjugate additions of organocopper reagents to N-enoyloxazolidinones
Williams, David R.,Kissel, William S.,Li, Jie Jack
, p. 8593 - 8596 (2007/10/03)
A survey of conjugate additions of Yamamoto organocopper reagents to N- enoyl-4-substituted oxazolidinones is reported. Diastereofacial selectivity is reversed for 4-phenyl and 4-benzyloxazolidinones of the same relative configuration. Alkenylcopper reage
