849403-59-4

Usage

Chemical Family

Pyrrole
A five-membered ring containing one nitrogen atom

Usage in Pharmaceutical Industry

Common
The compound is used in drug development and as an intermediate in the synthesis of various organic compounds

Potential Applications

Organic Chemistry Research, Agrochemicals, Specialty Chemicals
The compound's unique structure and properties make it useful in these areas

Importance

Diverse Potential Uses
The compound holds value in various industries due to its versatility and unique characteristics

Upstream product

• 371-40-4 4-fluoroaniline 
• 4653-08-1 4-oxo-4-thiophen-2-yl-butyric acid 

Downstream Products

• 1301717-99-6 1-(1-(4-fluorophenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl)-2-(thiazol-2-yl)diazene 
• 1312323-42-4 2-(benzo[d]thiazol-6-yl)-1-(1-(4-fluorophenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl)-diazene 
• 1312323-37-7 2-(benzo[d]thiazol-2-yl)-1-(1-(4-fluorophenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl)-diazene 

Relevant academic research and scientific papers

Modification of organic compounds with Lawesson's reagent

Application in organic synthesis of Lawesson's reagent, 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide, provides a possibility to replace an oxygen atom for a sulfur atom in the carbonyl group of ketones, esters, amides, in ether group, and also either to induce a rearrangement of the initial structure of organic compounds with or without inclusion of sulfur atoms or to lead to the formation of various types of organophosphorus compounds. The formed organosulfur compounds exhibit a wide range of biological action.

Arylamino-thieno-oxobutanainides under Lawesson's conditions: Competition between thienylpyrrole and bithiophene formation

1-Aryl-2-thienyl-substituted pyrroles and/or 5-arylamino-2,2′- bithiophenes were synthesized by treatment of arylamino-thieno-oxobutanamides with Lawesson's reagent. These in turn were prepared by direct amidation of 4-oxo-(2-thienyl)butanoic acid through DCC-BtOH mediated reactions.