849407-81-4

Upstream product

• 849407-79-0 C₆₉H₇₇N₅O₁₇ 
• 849407-76-7 (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-1-(4-Azido-butyl)-10-((2S,4S,6R)-4-dimethylamino-6-methyl-3-oxo-tetrahydro-pyran-2-yloxy)-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-octahydro-3,5-dioxa-1-aza-cyclopentacyclotetradecene-2,6,8,14-tetraone 
• 760981-81-5 11-N-(4-azido-butyl)-6-O-methyl-5-(2-acetyl-desosamynyl)-3-oxo-erythronolide A 11,12-carbamate 
• 849407-75-6 11-N-(4-azido-butyl)-6-O-methyl-5-O-desosaminyl-3-oxo-erythronolide A 11,12-carbamate 
• 760981-73-5 11-N-(4-azidobutyl)-6-O-methyl-5-hydroxy-3-oxoerythronolide A 11,12-carbamate 
• 217977-00-9 10,11-anhydro-2',4''-di-O-acetyl-12-O-(imidazol-1-ylcarbonyl)-6-O-methylerythromycin A 
• 849407-72-3 C₅₄H₈₆N₂O₁₈S 
• 849407-73-4 C₄₇H₇₉N₅O₁₅ 
• 849407-71-2 C₄₇H₈₀N₂O₁₆ 
• 849407-74-5 acetic acid 2-[1-(4-azido-butyl)-4-ethyl-8-hydroxy-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,14-trioxo-tetradecahydro-3,5-dioxa-1-aza-cyclopentacyclotetradecen-10-yloxy]-4-dimethylamino-6-methyl-tetrahydro-pyran-3-yl ester 
• 760981-72-4 1-(4-azido-butyl)-10-(4-dimethylamino-3-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-4-ethyl-8-hydroxy-11-methoxy-3a,7,9,11,13,15-hexamethyl-decahydro-3,5-dioxa-1-aza-cyclopentacyclotetradecene-2,6,14-trione 

Downstream Products

• 849407-84-7 C₅₆H₇₁N₅O₁₅ 

Relevant academic research and scientific papers

An efficient entry to new sugar modified ketolide antibiotics

A new and efficient route to a ketolide aglycon served as a basis for the unprecedented 5-O-glyco-modification of ketolide antibiotics. Combined with an effective copper-catalyzed triazole-forming reaction a series of novel and potent ketolide antibiotics

Synthesis and biological activity of new 5-O-sugar modified ketolide and 2-fluoro-ketolide antibiotics

A series of new triazole-containing ketolides and 2-fluoro-ketolides in which the 5-O-desosamine was replaced by unnatural sugars were synthesized and evaluated against relevant macrolide-sensitive and macrolide-resistant respiratory pathogens. Excellent