Cas 849409-77-4,(2R,4S,5S)-4-{[tert-butyl(dimethyl)silyl]oxy}-5-{[3-(1,1-dioxo-1,6-isothiazolidin-2-yl)benzoyl]amino}-2,7-dimethyloctanoic acid

849409-77-4

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Basic information

Product Name: (2R,4S,5S)-4-{[tert-butyl(dimethyl)silyl]oxy}-5-{[3-(1,1-dioxo-1,6-isothiazolidin-2-yl)benzoyl]amino}-2,7-dimethyloctanoic acid
Synonyms: (2R,4S,5S)-4-{[tert-butyl(dimethyl)silyl]oxy}-5-{[3-(1,1-dioxo-1,6-isothiazolidin-2-yl)benzoyl]amino}-2,7-dimethyloctanoic acid
CAS NO:849409-77-4
Molecular Formula:
Molecular Weight: 540.797
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (2R,4S,5S)-4-{[tert-butyl(dimethyl)silyl]oxy}-5-{[3-(1,1-dioxo-1,6-isothiazolidin-2-yl)benzoyl]amino}-2,7-dimethyloctanoic acid(CAS DataBase Reference)
NIST Chemistry Reference: (2R,4S,5S)-4-{[tert-butyl(dimethyl)silyl]oxy}-5-{[3-(1,1-dioxo-1,6-isothiazolidin-2-yl)benzoyl]amino}-2,7-dimethyloctanoic acid(849409-77-4)
EPA Substance Registry System: (2R,4S,5S)-4-{[tert-butyl(dimethyl)silyl]oxy}-5-{[3-(1,1-dioxo-1,6-isothiazolidin-2-yl)benzoyl]amino}-2,7-dimethyloctanoic acid(849409-77-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 849409-77-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 849409-77-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,4,0 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 849409-77:
(8*8)+(7*4)+(6*9)+(5*4)+(4*0)+(3*9)+(2*7)+(1*7)=214
214 % 10 = 4
So 849409-77-4 is a valid CAS Registry Number.

849409-77-4Upstream product

849409-77-4Downstream Products

849409-79-6 benzyl 4-[(4S,7R,9S)-9-((1S)-1-{[3-(1,1-dioxo-1,6-isothiazolidin-2-yl)benzoyl]amino}-3-methylbutyl)-4,7,11,11,12,12-hexamethyl-3,6-dioxo-10-oxa-2,5-diaza-11-silatridec-1-yl]benzoate

849409-77-4Relevant academic research and scientific papers

NOVEL SULFONE AMIDE DERIVATIVES CAPABLE OF INHIBITING BACE

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Page/Page column 40-41, (2010/02/11)

The present invention relates to novel derivatives of sulfone amide of Formula 1 as defined in this disclosure which inhibit the activity of BACE (or beta-secretase). These sulfone amide derivatives are useful for the treatment and prevention of Alzheimer's disease and related diseases caused by production of beta-amyloid, by inhibiting the activity of BACE.

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