849632-74-2

Upstream product

• 93138-61-5 C-(1-benzyl-pyrrolidin-3-yl)-methylamine 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 1426095-67-1 N-methyl-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide 
• 1303967-33-0 1-dimethylethyl 3(RS)-{[(1-methylethyl)amino]methyl}-1-pyrrolidinecarboxylate 
• 1426095-68-2 1,1-dimethylethyl (3RS)-[({[3-(methyloxy)-4-biphenylyl]carbonyl}amino)methyl]-1-pyrrolidinecarboxylate 
• 1426095-69-3 N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide 
• 1426094-94-1 N-{[(3RS)-1-cyclopropylcarbonyl-3-pyrrolidinyl]methyl}-N-methyl-4-biphenylcarboxamide 
• 1426094-95-2 N-{[1-cyclopropylcarbonyl-3(RS)-pyrrolidinyl]methyl}-N-methyl-3-(methyloxy)-4-biphenylcarboxamide 
• 1426095-26-2 N-{[(3RS)-1-cyclopropylcarbonyl-3-pyrrolidinyl]methyl}-N-(1-methylethyl)-4-biphenylcarboxamide 
• 1301188-37-3 2-(4-biphenylyl)-N-methyl-1-({(3RS)-1-[(3-methyl-5-isoxazolyl)carbonyl]-3-pyrrolidinyl}methyl)-1H-benzimidazole-6-carboxamide 
• 1301188-36-2 2-(4-biphenylyl)-1-({(3RS)-1-[(dimethylamino)carbonyl]-3-pyrrolidinyl}methyl)-N-methyl-1H-benzimidazole-6-carboxamide 
• 1301189-92-3 2-(4-biphenylyl)-N-methyl-1-[(3RS)-3-pyrrolidinylmethyl]-1H-benzimidazole-6-carboxamide 
• 1301189-91-2 1,1-dimethylethyl (3RS)-3-({2-(4-biphenylyl)-6-[(methylamino)carbonyl]-1H-benzimidazol-1-yl}methyl)-1-pyrrolidinecarboxylate 
• 1301189-89-8 2-(4-biphenylyl)-1-[((3R₅)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-3-pyrrolidinyl)methyl]-1H-benzimidazole-6-carboxylic acid 
• 1301189-87-6 3-{[((3RS)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-3-pyrrolidinyl)methyl]amino}-4-nitrobenzoic acid 
• 270912-72-6 tert-butyl 3-(aminomethyl)pyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

FATTY ACID SYNTHASE INHIBITORS

This invention relates to carboxamides and reverse carboxamides according to Formula (I) and the use of carboxamides and reverse carboxamides for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of carboxamides and reverse carboxamides in the treatment of cancer.

BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS

This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of benzimidazoles in the treatment of cancer.