93138-61-5

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
C-(1-BENZYL-PYRROLIDIN-3-YL)-METHYLAMINE is used as a compound in pharmaceutical research and drug development for its potential therapeutic properties. It may serve as a central nervous system stimulant, offering potential benefits in the treatment of various neurological and psychiatric disorders.
Used in the Treatment of Neurological and Psychiatric Disorders:
In the healthcare industry, C-(1-BENZYL-PYRROLIDIN-3-YL)-METHYLAMINE is used as a potential therapeutic agent for neurological and psychiatric disorders, due to its possible stimulant effects on the central nervous system.
Used in the Synthesis of Other Organic Compounds:
C-(1-BENZYL-PYRROLIDIN-3-YL)-METHYLAMINE also has applications in organic chemistry, where it is used as a building block or intermediate in the synthesis of other organic compounds, contributing to the development of new chemical entities with diverse applications.
Safety Considerations:
When handling C-(1-BENZYL-PYRROLIDIN-3-YL)-METHYLAMINE in a laboratory setting, it is crucial to follow proper safety protocols to ensure the well-being of researchers and the integrity of the experiments.

InChI:InChI=1/C12H18N2/c13-8-12-6-7-14(10-12)9-11-4-2-1-3-5-11/h1-5,12H,6-10,13H2/p+2/t12-/m1/s1

Upstream product

• 10603-52-8 1-benzyl-pyrrolidine-3-carbonitrile 
• 116041-19-1 1-benzyl 5-oxo-pyrrolidine-3-carboxamide 
• 7757-82-6 sodium sulfate 
• 5731-17-9 1-(Phenylmethyl)-3-pyrrolidinemethanol 

Downstream Products

• 1426095-26-2 N-{[(3RS)-1-cyclopropylcarbonyl-3-pyrrolidinyl]methyl}-N-(1-methylethyl)-4-biphenylcarboxamide 
• 1426094-95-2 N-{[1-cyclopropylcarbonyl-3(RS)-pyrrolidinyl]methyl}-N-methyl-3-(methyloxy)-4-biphenylcarboxamide 
• 1426094-94-1 N-{[(3RS)-1-cyclopropylcarbonyl-3-pyrrolidinyl]methyl}-N-methyl-4-biphenylcarboxamide 
• 1426095-69-3 N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide 
• 1426095-68-2 1,1-dimethylethyl (3RS)-[({[3-(methyloxy)-4-biphenylyl]carbonyl}amino)methyl]-1-pyrrolidinecarboxylate 
• 1303967-33-0 1-dimethylethyl 3(RS)-{[(1-methylethyl)amino]methyl}-1-pyrrolidinecarboxylate 
• 1426095-67-1 N-methyl-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide 
• 1301188-37-3 2-(4-biphenylyl)-N-methyl-1-({(3RS)-1-[(3-methyl-5-isoxazolyl)carbonyl]-3-pyrrolidinyl}methyl)-1H-benzimidazole-6-carboxamide 
• 1301188-36-2 2-(4-biphenylyl)-1-({(3RS)-1-[(dimethylamino)carbonyl]-3-pyrrolidinyl}methyl)-N-methyl-1H-benzimidazole-6-carboxamide 
• 1301189-92-3 2-(4-biphenylyl)-N-methyl-1-[(3RS)-3-pyrrolidinylmethyl]-1H-benzimidazole-6-carboxamide 
• 1301189-91-2 1,1-dimethylethyl (3RS)-3-({2-(4-biphenylyl)-6-[(methylamino)carbonyl]-1H-benzimidazol-1-yl}methyl)-1-pyrrolidinecarboxylate 
• 1301189-89-8 2-(4-biphenylyl)-1-[((3R₅)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-3-pyrrolidinyl)methyl]-1H-benzimidazole-6-carboxylic acid 
• 1301189-87-6 3-{[((3RS)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-3-pyrrolidinyl)methyl]amino}-4-nitrobenzoic acid 
• 270912-72-6 tert-butyl 3-(aminomethyl)pyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

Indole, azaindole and related heterocyclic pyrrolidine derivatives

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with amido piperazine derivatives. These compounds possess unique antiviral activity

Pyrrolidine derivatives-CCR-3 receptor antagonists

This invention relates to certain 3-aminomethylpyrrolidine derivatives of Formula (I): that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.

Synthesis and pharmacological evaluation of carboxamide derivatives as selective serotoninergic 5-HT4 receptor agonists

A number of new carboxamide derivatives were synthesized. The affinity of these compounds for the serotoninergic 5-HT4 receptor was evaluated by use of radioligand-binding techniques. The agonistic activity was evaluated as the contractile effect of the ascending colon isolated from guinea-pigs. Among these compounds, 4-amino-5-chloro-2-methoxy-N-[l-[2- [(methylsulfonyl)amino]ethly]-4piperidinylmethyl]benzamide (24) showed a high affinity for the 5-HT4 receptor (Ki = 9.6 nM). Compound 24 displayed a higher affinity for 5-HT4 receptors than the other receptors, including, 5- HT3 and dopamine D2 receptors. In addition, compound 24 was confirmed to be a potent 5-HT4 receptor agonist (ED50 = 7.0 nM). An interaction model between compound 24 and 5-HT4 receptor was proposed.