849670-36-6

Basic information

• Product Name: [4-(R)-(5-fluoro-3,3-dimethyl-2,3-dihydro-indol-1-yl)-tetrahydro-furan-3-(R)-yl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester
• Synonyms: [4-(R)-(5-fluoro-3,3-dimethyl-2,3-dihydro-indol-1-yl)-tetrahydro-furan-3-(R)-yl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester
• CAS NO: 849670-36-6
• Molecular Weight: 517.641
• Mol File: 849670-36-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [4-(R)-(5-fluoro-3,3-dimethyl-2,3-dihydro-indol-1-yl)-tetrahydro-furan-3-(R)-yl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(R)-(5-fluoro-3,3-dimethyl-2,3-dihydro-indol-1-yl)-tetrahydro-furan-3-(R)-yl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester(849670-36-6)
• EPA Substance Registry System: [4-(R)-(5-fluoro-3,3-dimethyl-2,3-dihydro-indol-1-yl)-tetrahydro-furan-3-(R)-yl]-carbamic acid 1-(S)-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester(849670-36-6)

Safety Data

• Hazardous Substances Data: 849670-36-6(Hazardous Substances Data)

Upstream product

• 849671-39-2 (S)-carbonic acid 1-cyclohexylmethyl-2-morpholin-4-yl-2-oxo-ethyl ester 4-nitro-phenyl ester 
• 225642-33-1 5-fluoro-3,3-dimethylindoline 
• 216086-95-2 (S)-3-cyclohexyl-2-hydroxy-1-morpholin-4-yl-propan-1-one 
• 849671-41-6 1-(4-(R)-azido-tetrahydro-furan-3-(R)-yl)-5-fluoro-3,3-dimethyl-2,3-dihydro-1H-indole 
• 27527-05-5 L-cyclohexylalanine 

Relevant articles and documents

INHIBITORS OF CATHEPSIN S

The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.