849676-34-2

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 849676-28-4 (E)-2-bromo-6-methylhept-2-ene 
• 849676-33-1 4(S)-4-(tert-butyl-dimethyl-silanyloxymethyl)-cyclohex-2-enone 
• 541-28-6 isopentyl iodide 
• 38580-68-6 4-hydroxymethyl-cyclohexanone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 688809-70-3 4-(tert-butyl-dimethyl-silanyloxymethyl)-cyclohexanone 

Downstream Products

• 849676-35-3 2(S)-3(S)-4(S)-3-(1,5-dimethyl-hex-1-enyl)-2-hydroxy-4-(tert-butyl-dimethyl-silanyloxymethyl)-cyclohexanone 
• 849676-38-6 1(S)-2(S)-3(S)-2-(1,5-dimethyl-hex-1-enyl)-3-methoxy-4-oxo-cyclohexanecarbaldehyde 
• 872603-31-1 2(S)-3(S)-4(S)-3-(1,5-dimethyl-hex-1-enyl)-2-methoxy-4-(1-hydroxy-ethyl)-cyclohexanone 
• 849676-37-5 2(S)-3(S)-4(S)-3-(1,5-dimethyl-hex-1-enyl)-4-hydroxymethyl-2-methoxy-cyclohexanone 
• 849676-39-7 2(S)-3(S)-4(S)-3-(1,5-dimethyl-hex-1-enyl)-2-methoxy-4-(2,2,2-trifluoro-acetyl)-cyclohexanone 
• 849676-36-4 2(S)-3(S)-4(S)-3-(1,5-dimethyl-hex-1-enyl)-4-(tert-butyl-dimethyl-silanyloxymethyl)-2-methoxy-cyclohexanone 
• 849676-41-1 1(R)-2(S)-3(S)-4(S)-3-(1,5-dimethyl-hex-1-enyl)-4-(tert-butyl-dimethyl-silanyloxymethyl)-2-methoxy-cyclohexanol 
• 849676-42-2 (E)-3-(4-Methoxy-phenyl)-acrylic acid (1R,2S,3S,4S)-3-((E)-1,5-dimethyl-hex-1-enyl)-4-hydroxymethyl-2-methoxy-cyclohexyl ester 
• 872603-35-5 2(S)-3(S)-4(S)-3-(1,5-dimethyl-hex-1-enyl)-2-hydroxy-4-(tert-butyl-dimethyl-silanyloxymethyl)-cyclohexanone 

Relevant academic research and scientific papers

Novel Angiogenesis inhibitors and pharmaceutical/cosmetic applications thereof

Novel derivatives of fumagalone have the general formula (I): and are useful angiogenes is inhibitors; these can be formulated into pharmaceutical compositions suited for human or veterinary medicine, or can be formulated into cosmetic compositions.

Enantioselective approaches to potential MetAP-2 reversible inhibitors

(Chemical Equation Presented) Enantioselective deprotonation of 4-substituted cyclohexanones and highly stereoselective conjugate addition of higher order mixed cuprates were the key steps in a concise synthesis of fumagalone-related molecules. The origin