849773-85-9

Upstream product

• 727726-31-0 [(2R)-2-methyl-3-(phenylmethoxy)-1-propyl][2-(phenylmethyl)-1,3-dithian-2-yl]diphenylsilane 
• 727726-40-1 [(2R)-2-methyl-3-(phenylmethoxy)-1-propyl][2-phenyl-1-oxoethyl]diphenylsilane 
• 727726-42-3 [(2R)-2-methyl-3-(phenylmethoxy)-1-propyl][2-phenyl-1-hydroxyethyl]diphenylsilane 
• 727726-30-9 [2-(phenylmethyl)-1,3-dithian-2-yl]fluorodiphenylsilane 
• 31593-52-9 2-benzyl-1,3-dithiane 
• 56850-58-9 methyl (2R)-3-(benzyloxy)-2-methylpropanoate 
• 90344-49-3 (2R)-3-iodo-2-methylpropyl benzyl ether 
• 312-40-3 difluorodiphenylsilane 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 63930-46-1 (S)-3-benzyloxy-2-methylpropan-1-ol 
• 727726-44-5 2-[[1-[(2R)-2-methyl-3-(phenylmethoxy)-1-propyl]diphenylsilyl]-2-phenylethyl]-1H-isoindole-1,3(2H)-dione 

Downstream Products

• 727726-47-8 [(2R)-2-methyl-3-hydroxy-1-propyl][(1R)-1-(benzoylamino)-2-phenylethyl]diphenylsilane 
• 727726-48-9 [(2R)-2-methyl-3-hydroxy-1-propyl][(1S)-1-(benzoylamino)-2-phenylethyl]diphenylsilane 
• 727726-54-7 (2R)-3-[[(1R)-1-(benzoylamino)-2-phenylethyl]diphenylsilyl]-2-methylpropanoic acid 
• 727726-55-8 (2R)-3-[[(1S)-1-(benzoylamino)-2-phenylethyl]diphenylsilyl]-2-methylpropanoic acid 
• 727726-57-0 (S)-1-{(R)-3-[((R)-1-benzamido-2-phenylethyl)difluoro sily-l]-2-methylpropanoyl}pyrrolidine-2-carboxylic acid 
• 727726-58-1 (S)-1-{(R)-3-[((S)-1-benzamido-2-phenylethyl)difluoro sily-l]-2-methylpropanoyl}pyrrolidine-2-carboxylic acid 
• 727726-50-3 (2R)-1-[3-[[(1R)-1-(benzoylamino)-2-phenylethyl]diphenylsilyl]-2-methyl-1-oxopropyl]-L-proline 1,1-dimethylethyl ester 
• 727726-51-4 (2R)-1-[3-[[(1S)-1-(benzoylamino)-2-phenylethyl]diphenylsilyl]-2-methyl-1-oxopropyl]-L-proline 1,1-dimethylethyl ester 
• 727726-46-7 [(2R)-2-methyl-3-(phenylmethoxy)-1-propyl][1-(benzoylamino)-2-phenylethyl]diphenylsilane 

Relevant academic research and scientific papers

Silanediol inhibitors of angiotensin-converting enzyme. Synthesis and evaluation of four diastereomers of Phe[Si]Ala dipeptide analogues

Four stereoisomers of a Phe-Ala silanediol dipeptide mimic have been evaluated as inhibitors of angiotensin-converting enzyme (ACE) and compared to ketone-based inhibitors reported by Almquist et al. One stereogenic center of the isomers was derived from

Silanediol peptidomimetics. Evaluation of four diastereomeric ACE inhibitors

Four diastereomers of a Phe-Ala peptide mimic incorporating a central silanediol group have been individually prepared and tested as inhibitors of angiotensin-converting enzyme (ACE). Three of the silanediols exhibit levels of inhibition that are similar