84980-50-7

Upstream product

• 2888-64-4 diazepam 4-oxide 
• 84980-46-1 10-chloro-1,2,7,11b-tetrahydro-r-2-methoxycarbonyl-7-methyl-c-11b-phenylisoxazolo<2,3-d><1,4>benzodiazepin-6(5H)-one 

Relevant academic research and scientific papers

Synthesis and Stereochemical Characterisation of 1,2,7,11b-Tetrahydropyrrolobenzodiazepine-3,6(5H)-diones, obtained via Raney Nickel Hydrogenation of Tetrahydroisoxazolobenzodiazepinones

Catalytic hydrogenation (Raney nickel) of 2-alkoxycarbonyl-1,2,7,11b-tetrahydroisoxazolobenzodiazepine-3,6(5H)-ones (1) produces 1,2,7,11b-tetrahydro-2-hydroxypyrrolobenzodiazepine-3,6(5H)-diones (2a-c).Their stereochemical charact

Tetrahydroisoxazolobenzodiazepinone Ring System: Synthesis, Stereochemistry, and Conformation

Reaction of 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide (diazepam 4-oxide) with acrylic esters produces annelated substituted isoxazolidines: 1,3-dipolar cycloaddition is regiospecific, the adducts with methyl crotonate showi