2888-64-4

Basic information

• Product Name: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-benzo-1,4-diazepin-2-one 4-oxide
• Synonyms: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-benzo-1,4-diazepin-2-one 4-oxide;7-Chloro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one 4-oxide;Diazepam N-oxide
• CAS NO: 2888-64-4
• Molecular Formula: C₁₆H₁₃ClN₂O₂
• Molecular Weight: 300.73962
• EINECS: 220-756-7
• Mol File: 2888-64-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 179-180 °C(Solv: ethanol (64-17-5))
• Boiling Point: 579.4°Cat760mmHg
• Flash Point: 304.2°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 2.03E-13mmHg at 25°C
• Refractive Index: 1.672
• PKA: 0.56±0.20(Predicted)
• CAS DataBase Reference: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-benzo-1,4-diazepin-2-one 4-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-benzo-1,4-diazepin-2-one 4-oxide(2888-64-4)
• EPA Substance Registry System: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-benzo-1,4-diazepin-2-one 4-oxide(2888-64-4)

Safety Data

• Hazardous Substances Data: 2888-64-4(Hazardous Substances Data)

Usage

General Description

7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-benzo-1,4-diazepin-2-one 4-oxide, also known as Clopenthixol, is a chemical compound with a complex molecular structure. It belongs to the class of benzodiazepines and is used as an antipsychotic medication for the treatment of schizophrenia and other psychotic disorders. Clopenthixol works by affecting the neurotransmitters in the brain, particularly dopamine and serotonin, to help regulate mood and behavior. It is available in various forms, including oral tablets and injectable solutions, and is typically prescribed by healthcare professionals for the management of severe mental illnesses. Due to its psychoactive properties, Clopenthixol should be used with caution and under the supervision of a qualified healthcare provider.

InChI:InChI=1/C16H13ClN2O2/c1-18-14-8-7-12(17)9-13(14)16(19(21)10-15(18)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3

Upstream product

• 439-14-5 diazepam 
• 64741-01-1 m-chloroperoxybenzoic acid 
• 108-20-3 di-isopropyl ether 

Downstream Products

• 80483-99-4 ethyl α-benzoyl-7-chloro-3,4-dihydro-4-methyl-3-oxo-1(2H)-quinoxalineacrylate 
• 60628-55-9 3-fluoro-1,3-dihydro-1-methyl-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 846-50-4 temazepam 
• 84980-51-8 10-chloro-1,2,7,11b-tetrahydro-r-2-hydroxy-t-2,7-dimethyl-t-11b-phenylpyrrolo<1,2-d><1,4>benzodiazepine-3,6(5H)-dione 
• 84980-50-7 10-chloro-1,2,7,11b-tetrahydro-r-2-hydroxy-7-methyl-t-11b-phenylpyrrolo<1,2-d><1,4>benzodiazepine-3,6(5H)-dione 
• 181648-06-6 [3-2H₂]diazepam 4-oxide 
• 84980-48-3 10-chloro-1,2,7,11b-tetrahydro-r-2-methoxycarbonyl-t-2,7-dimethyl-c-11b-phenylisoxazolo<2,3-d><1,4>benzodiazepin-6(5H)-one 
• 84980-46-1 10-chloro-1,2,7,11b-tetrahydro-r-2-methoxycarbonyl-7-methyl-c-11b-phenylisoxazolo<2,3-d><1,4>benzodiazepin-6(5H)-one 
• 60628-73-1 7-chloro-3-fluoro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one N⁴-oxide 
• 55524-37-3 ethyl 10-chloro-5,6,7,11b-tetrahydro-7-methyl-6-oxo-11b-phenylisoxazolo<2,3-d><1,4>benzodiazepine-1-carboxylate 
• 80483-98-3 <α-(7-chloro-3,4-dihydro-4-methyl-3-oxo-1(2H)-quinoxazolinyl)benzylidene>malonaldehydic acid ethyl ester 
• 80484-00-0 6-chloro-3,4-dihydro-1-methyl-2(1H)-quinoxazolinone 

Relevant articles and documents

Process for catalyzing the oxidation of organic compounds

Oxidation of organic compounds is catalyzed by addition of a catalytic amount of a metalloporphyrin in a non-reactive aprotic solvent.