849814-34-2

Upstream product

• 616888-59-6 2(S)-benzyloxycarbonylamino-3-(2-benzyloxy-5-iodophenyl)propionic acid (2-trimethylsilyl)ethyl ester 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 856222-50-9 2-trimethylsilyl-ethyl (2S)-3-(3'-{(2S)-3-benzyloxy-2-[(tert-butoxycarbonyl)amino]-3-oxo-propyl}-4'-fluoro-4-hydroxy-biphenyl-3-yl)-2-{[(benzyloxy)carbonyl]amino}-propanoate 
• 856222-60-1 methyl (2S)-3-(4'-(benzyloxy)-3'-{(2S)-2-{[(benzyloxy)carbonyl]amino}-3-oxo-3-[2-(trimethylsilyl)ethoxy]propyl}-4-fluorobiphenyl-3-yl)-2-[(tert-butoxycarbonyl)(methyl)amino]propanoate 
• 636594-96-2 2-(trimethylsilyl)ethyl 2-(S)-benzyloxycarbonylamino-3-[3'[-2-[tert-butoxycarbonylamino(3-amino-[1-(S)-benzyloxy-1-oxo-2-phenylethyl]-3-oxopropyl)]-4,4'-bis(benzyloxy)-1,1'-biphenyl-3-yl]]propanoate 
• 868073-46-5 2-(trimethylsilyl)ethyl 2-{[(benzyloxy)carbonyl]amino}-3-(4,4'-bis(benzyloxy)-3'-{(2S)-3-({(1S)-2-(benzyloxy)-1-[4-(benzyloxy)benzyl]-2-oxoethyl}amino)-2-[(tert-butoxycarbonyl)amino]-3-oxopropyl}biphenyl-3-yl)propanoate 

Relevant academic research and scientific papers

Antibacterial amide macrocycles

The invention relates to antibacterial amide macrocycles, to methods for the production thereof, and to the use of the same for producing pharmaceuticals for the treatment and/or prophylaxis of illness, especially bacterial infections.

Antibacterial macrocycles with substituted biphenyl

The invention relates to antibacterial macrocycles with substituted biphenyl and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially of bacterial infections.

ANTIBACTERIAL AMIDE MACROCYCLES II

The invention relates to antibacterial amide macrocycles and to methods for their production. The invention also relates to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially of bacterial infections.