849818-58-2 Usage
Uses
Used in Pharmaceutical Industry:
6-(TrifluoroMethyl)quinoline-2-carboxylic acid is used as a precursor in the synthesis of various functionalized quinoline derivatives for the development of biologically active compounds. Its structural properties make it a promising candidate for the creation of new pharmaceuticals with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 6-(TrifluoroMethyl)quinoline-2-carboxylic acid serves as a building block for the development of new agrochemicals. Its unique structure allows for the design of compounds with specific pesticidal or herbicidal properties, contributing to more effective and targeted crop protection.
Used in Organometallic Chemistry:
6-(TrifluoroMethyl)quinoline-2-carboxylic acid is used as a ligand in organometallic chemistry. Its ability to form stable complexes with metal ions makes it a valuable component in the synthesis of organometallic compounds with potential applications in catalysis, materials science, and other areas.
Environmental Research:
6-(TrifluoroMethyl)quinoline-2-carboxylic acid's presence in the environment and its potential effects on human health and the ecosystem are of interest for further research and understanding. Studying its environmental fate, toxicity, and potential impact can help in assessing risks and developing strategies for safe handling and disposal.
Check Digit Verification of cas no
The CAS Registry Mumber 849818-58-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,8,1 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 849818-58:
(8*8)+(7*4)+(6*9)+(5*8)+(4*1)+(3*8)+(2*5)+(1*8)=232
232 % 10 = 2
So 849818-58-2 is a valid CAS Registry Number.
849818-58-2Relevant academic research and scientific papers
Discovery and efficient synthesis of a biologically active alkaloid inspired by thiostrepton biosynthesis
Zheng, Qingfei,Wang, Shoufeng,Liu, Wen
, p. 7686 - 7690 (2014/12/10)
Thiostrepton, a natural peptide macrocycle, is of great interest due to its structural complexity and numerous biological activities, including anti-bacterial, anti-tumor, and anti-plasmodial activities. The quinaldic acid (QA) moiety-containing side ring (loop 2) was proven to play an important role in carrying out these functions. Previously, we proposed biosynthetic logic for thiostrepton loop 2 and demonstrated the formation mechanism of QA. Herein, we report the discovery and efficient synthesis of a biologically active alkaloid, that is, a key intermediate involved in the thiostrepton biosynthetic pathway. A chemo-enzymatic method was performed to synthesize the molecule, and a series of analogs were prepared for bioassays, which included the examination of anti-bacterial and anti-tumor activities.
CETP INHIBITORS AND METABOLITES THEREOF
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Page/Page column 32-33, (2010/02/11)
Compounds resulting from the administration of torcetrapib to a mammal, and the use of such compounds as an indicator or biomarker to the presence or exposure of torcetrapib in the plasma of a mammal including humans. The invention is also directed to cholesteryl ester transfer protein (CET P) inhibitors, pharmaceutical compositions containing such inhibitors and the usi-, of such inhibitors to elevate cert in plasma lipid levels, including high den~;ity lipoprotein (HDL)-cholesterol and t lower certain other plasma lipid levels, such as low density lipoprotein (LDL)-chole terol and triglycerides.
