88845-76-5Relevant academic research and scientific papers
Amino acids and peptides. IX. Synthesis of cysteine-containing peptide fragments related to human hepatic metallothionein II (hMT II) and determination of their heavy metal-binding properties
Ohta,Okada,Tanaka
, p. 3094 - 3103 (2007/10/02)
Eight kinds of cysteine-containing peptides related to human hepatic metallothionein were synthesized by conventional methods. The metal-binding properties of these peptides with Zn2+ and Cd2+ were indicated by an increase of ultraviolet absorbance resulting from mercaptide formation. The Cd-binding activities of various peptides obtained here were assessed by measuring the increase in absorbance of mercaptide at 250 mm as a function of the concentration of Cd. The binding abilities of the peptides with Cd differed substantially.
