849928-69-4

Upstream product

• 849928-64-9 tert-butyl (2S,3R)-3-(benzyloxy)-2-(hydroxymethyl)piperidine-1-carboxylate 
• 448896-88-6 (8R,8aS)-8-hydroxy-8,8a-dihydro-1H-oxazolo[3,4-a]pyridin-3(5H)-one 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 849928-65-0 (2R,3R)-3-Benzyloxy-2-formyl-piperidine-1-carboxylic acid tert-butyl ester 
• 849928-63-8 (8R,8aS)-8-benzyloxyhexahydrooxazolo[3,4-a]pyridin-3-one 
• 849928-62-7 (8R,8aS)-8-hydroxyhexahydrooxazolo[3,4-a]pyridin-3-one 

Downstream Products

• 849928-71-8 (1S,2R,8R,8aS)-8-benzyloxy-1,2-dihydroxyhexahydroindolizin-3-one 

Relevant academic research and scientific papers

General approach to glycosidase inhibitors. Enantioselective synthesis of deoxymannojirimycin and swainsonine

(Chemical Equation Presented) Deoxymannojirimycin (2) and swainsonine (4) have been synthesized from each enantiomer of the same bicyclic carbarnate precursor 7. The key intermediate was prepared by a simple and efficient three-step synthesis involving RCM of the diene 8, which in turn is easily accessible in any configuration from enantiomerically enriched 2,3-epoxy-4-penten-1-ol 9.