849928-69-4Relevant articles and documents
General approach to glycosidase inhibitors. Enantioselective synthesis of deoxymannojirimycin and swainsonine
Martin, Ruben,Murruzzu, Caterina,Pericas, Miquel A.,Riera, Antoni
, p. 2325 - 2328 (2007/10/03)
(Chemical Equation Presented) Deoxymannojirimycin (2) and swainsonine (4) have been synthesized from each enantiomer of the same bicyclic carbarnate precursor 7. The key intermediate was prepared by a simple and efficient three-step synthesis involving RCM of the diene 8, which in turn is easily accessible in any configuration from enantiomerically enriched 2,3-epoxy-4-penten-1-ol 9.