84993-20-4Relevant academic research and scientific papers
Synthesis and applications of a fluorous THP protective group
Wipf, Peter,Reeves, Jonathan T.
, p. 4649 - 4652 (1999)
A recyclable fluorous labeled THP protecting group has been developed that allows for simple purification of small molecules by liquid-liquid extraction with FC-72/MeCN, and of larger or more polar molecules by solid phase extraction with fluorous reverse phase silica gel. In addition, we report a new glycosylation method which uses the Cp2ZrCl2-AgClO4 reagent system to activate an anomeric sulfoxide.
