85-27-8

Basic information

• Product Name: 4-(alpha-Methylbenzyl)resorcinol
• Synonyms: 4-(1-Phenylethyl)benzene-1,3-diol;4-(1-Phenylethyl)resorcin;4-(1-Phenylethyl)resorcinol;4-(alpha-Methylbenzyl)resorcinol;1,3-Benzenediol, 4-(1-phenylethyl)-;4-(1-phenylethy)-1,3-benzenediol;4-(1-phenylethyl)-1,3-Benzenediol;Phenylethyl Resorcinol
• CAS NO: 85-27-8
• Molecular Formula: C₁₄H₁₄O₂
• Molecular Weight: 214.25976
• EINECS: 480-070-0
• Product Categories: OLED materials,pharm chemical,electronic
• Mol File: 85-27-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 78-79℃
• Boiling Point: 244°C/12mmHg(lit.)
• Appearance: /
• Density: 1.171
• Vapor Pressure: 0Pa at 20℃
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• PKA: 9.77±0.40(Predicted)
• Water Solubility: 3.85g/L at 20℃
• CAS DataBase Reference: 4-(alpha-Methylbenzyl)resorcinol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(alpha-Methylbenzyl)resorcinol(85-27-8)
• EPA Substance Registry System: 4-(alpha-Methylbenzyl)resorcinol(85-27-8)

Safety Data

• Hazardous Substances Data: 85-27-8(Hazardous Substances Data)

Usage

Uses

4-(1-Phenylethyl)-1,3-benzenediol is an novel active ingredient of highly efficient skin lightening agents.

Flammability and Explosibility

Nonflammable

Upstream product

• 100-42-5 styrene 
• 108-46-3 recorcinol 
• 150-19-6 O-methylresorcine 
• 98-85-1 1-Phenylethanol 
• 151-10-0 1,3-Dimethoxybenzene 
• 1445-91-6 (S)-1-phenylethanol 

Downstream Products

• 54459-34-6 2,4-dimethoxy-1-(1-phenylethyl)benzene 

Relevant articles and documents

Based on H2 SO4 - SiO2 The solid acid catalyst which is suitable for industrial preparation phenylethyl resorcinol (by machine translation)

The invention discloses a based on H2 SO4 - SiO2 The solid acid catalyst which is suitable for industrial preparation phenylethyl resorcinol method. In the efficient solid acid H2 SO4 - SiO2 Under the catalytic action, one-step synthesis of the system results in the benzene ethyl resorcinol. The method of the invention can be applied to industrial production, efficient manufacturing phenylethyl resorcinol, to meet the needs of high-efficient catalyst has the advantage of conditions, recycled resorcinol raw materials and organic solvent realize and simplify the process route, environmental protection is reduced pressure. (by machine translation)

Hydroarylation of styrenes with electron-rich arenes over acidic ion-exchange resins

A series of acidic cation-exchange resins were used for the hydroarylation of resorcinol with styrene, in which resin D072 exhibited the excellent catalytic performance in this reaction with 99% conversion of styrene and 90% selectivity of 4-(1-phenylethyl)resorcinol. It was applied to the hydroarylation of various electron-rich arenes with styrenes, and the hydroarylated products were quantitatively obtained. This catalyst could be used for four consecutive runs with slight decrease in activity. The hydroarylation of resorcinol with styrene over resin D072 in a fixed bed was completed effectively with 94% selectivity and 99% conversion, and this green continuous process is potentially applicable to large-scale productions.

Antioxidant activities of dihydric phenol derivatives for the autoxidation of tetralin

The antioxidant activities of dihydric phenols, such as catechol, resorcinol, and hydroquinone, and their twenty-three alkyl and benzyl substituted derivatives were evaluated by means of an oxygen-absorption method at 60°C for determining the oxidation of tetralin. Catechols exhibited a much higher stoichiometric factor (2.0-2.3) compared with those of other compounds. The stoichiometric factors of hydroquinones (0.6-1.1) are almost half those of catechols, and are lower for the resorcinols (0.3-0.6). In addition, the rates of oxidation during the induction period (R(inh)) were 1.1-1.6 x 10-6, 3.0-3.8 x 10-6, and 13.3-18.4 x 10-6 M min-1 for catechols, hydroquinones, and resorcinols, respectively. According to these results, catechols and hydroquinones are efficient antioxidants, and their activities may be dependent on the stability of phenoxyl radicals as oxidation products due to the formation of the quinone structure. Furthermore, the stability of phenoxyl radicals derived from catechols is higher than that of those from hydroquinones. In spite of having two OH substituents, resorcinols behave as monohydric phenols in the reaction with peroxyl radicals.