85-85-8 Usage
Uses
1-(2-Pyridylazo)-2-naphthol is an indicator of transition metals. 1-(2-Pyridylazo)-2-naphthol is an indicator in complexometry and a reagent for the extraction and spectrophotometric determination of many transition metals. Dyes and metabolites.
General Description
1-(2-Pyridylazo)-2-naphthol (PAN), an orange colored dye, is commonly used as an acid-base indicator. It can form chelates with metal ions, which makes it a valuable indicator in complexometric titrations. PAN is also a spectrophotometric reagent, which can extract metal chelates into an organic solvent.
Agricultural Uses
1-(2-Pyridylazo)-2-naphthol is a hard stratum of strongly compacted soil caused by continual plowing to the same depth of hardened soil which has high clay content. The precipitated iron and silicates cement the soil particles and form pans. 1-(2-Pyridylazo)-2-naphthol often impede drainage and root growth. It can be broken up using a subsoiler .
Purification Methods
Purify PAN by repeated crystallisation from EtOH or MeOH. It can also be purified by sublimation under vacuum. Purity can be checked by TLC using a mixed solvent (pet ether/Et2O/EtOH; 10:10:1) on a silica gel plate. It has pK1 1.9 and pK2 12.2 in 20% aqueous ethoxyethanol. It chelates with copper [Pease & Williams Anal Chem 31 1046 1959]. [Beilstein 22 I 694, 22 III/IV 7073, 22/4 V 618.]
Check Digit Verification of cas no
The CAS Registry Mumber 85-85-8 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 85-85:
(4*8)+(3*5)+(2*8)+(1*5)=68
68 % 10 = 8
So 85-85-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H11N3O/c19-13-9-8-11-5-1-2-6-12(11)15(13)18-17-14-7-3-4-10-16-14/h1-10,19H
85-85-8Relevant articles and documents
Azo compounds reducing formation and toxicity of amyloid beta aggregation intermediates
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, (2011/10/12)
The present invention relates to compounds suitable as modulators of protein misfolding and/or protein aggregation. The compounds are particularly suitable as inhibitors of amyloid aggregate formation and/or modulators of amyloid surface properties, and/or as activators of degradation or reduction of amyloid aggregates.
IMPROVED SYNTHESES OF 4-(2-PYRIDYLAZO)-1,3-BENZENEDIOL (PAR) AND 1-(2-PYRIDYLAZO)-2-NAPHTHOL (PAN)
Wiejak, Stanislaw,Pasternak, Ewaryst E.,Tomasik, Piotr
, p. 895 - 897 (2007/10/02)
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Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator
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, (2008/06/13)
An evaporator system adapted for emitting insect killing vapors of an insecticide therefrom and comprising a liquid or solid composition enclosed therein, said insecticide consisting in at least one volatile phosphoric acid ester which is stabilized by at least one diazene compound.
