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1-(2-Pyridylazo)-2-naphthol is an organic compound that serves as a versatile chemical reagent and indicator, characterized by its ability to form complexes with transition metals and its application in various analytical techniques.

85-85-8

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85-85-8 Usage

Uses

Used in Analytical Chemistry:
1-(2-Pyridylazo)-2-naphthol is used as an indicator for the complexometric titration of transition metals, such as copper, iron, and zinc. It forms colored complexes with these metals, allowing for their detection and quantification through visual observation or spectrophotometry.
Used in Environmental Science:
1-(2-Pyridylazo)-2-naphthol is used as a reagent for the extraction and spectrophotometric determination of trace amounts of transition metals in environmental samples, such as water, soil, and air. This helps in assessing the presence and concentration of potentially harmful metal contaminants.
Used in Pharmaceutical Industry:
1-(2-Pyridylazo)-2-naphthol is used as a reagent in the development and analysis of metal-based pharmaceutical compounds, aiding in the detection and quantification of metal ions in drug formulations.
Used in Research and Development:
1-(2-Pyridylazo)-2-naphthol is employed as a research tool in the synthesis and study of metal complexes, providing insights into their properties, stability, and potential applications in various fields, including catalysis, materials science, and medicine.

Purification Methods

Purify PAN by repeated crystallisation from EtOH or MeOH. It can also be purified by sublimation under vacuum. Purity can be checked by TLC using a mixed solvent (pet ether/Et2O/EtOH; 10:10:1) on a silica gel plate. It has pK1 1.9 and pK2 12.2 in 20% aqueous ethoxyethanol. It chelates with copper [Pease & Williams Anal Chem 31 1046 1959]. [Beilstein 22 I 694, 22 III/IV 7073, 22/4 V 618.]

Check Digit Verification of cas no

The CAS Registry Mumber 85-85-8 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 85-85:
(4*8)+(3*5)+(2*8)+(1*5)=68
68 % 10 = 8
So 85-85-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H11N3O/c19-13-9-8-11-5-1-2-6-12(11)15(13)18-17-14-7-3-4-10-16-14/h1-10,19H

85-85-8 Well-known Company Product Price

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  • Alfa Aesar

  • (A17475)  1-(2-Pyridylazo)-2-naphthol, 98%   

  • 85-85-8

  • 1g

  • 225.0CNY

  • Detail
  • Alfa Aesar

  • (A17475)  1-(2-Pyridylazo)-2-naphthol, 98%   

  • 85-85-8

  • 5g

  • 713.0CNY

  • Detail
  • Alfa Aesar

  • (A17475)  1-(2-Pyridylazo)-2-naphthol, 98%   

  • 85-85-8

  • 25g

  • 2729.0CNY

  • Detail
  • Sigma

  • (82960)  1-(2-Pyridylazo)-2-naphthol  for spectrophotometric det. of metal ions, ≥97.0%

  • 85-85-8

  • 82960-1G

  • 372.06CNY

  • Detail
  • Sigma

  • (82960)  1-(2-Pyridylazo)-2-naphthol  for spectrophotometric det. of metal ions, ≥97.0%

  • 85-85-8

  • 82960-5G

  • 1,467.18CNY

  • Detail
  • Sigma-Aldrich

  • (101036)  1-(2-Pyridylazo)-2-naphthol  indicator grade

  • 85-85-8

  • 101036-5G

  • 1,354.86CNY

  • Detail
  • Sigma-Aldrich

  • (101036)  1-(2-Pyridylazo)-2-naphthol  indicator grade

  • 85-85-8

  • 101036-25G

  • 4,662.45CNY

  • Detail

85-85-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-Pyridylazo)-2-naphthol

1.2 Other means of identification

Product number -
Other names 1-(2'-pyridylazo)-2-naphthol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:85-85-8 SDS

85-85-8Relevant academic research and scientific papers

Azo compounds reducing formation and toxicity of amyloid beta aggregation intermediates

-

, (2011/10/12)

The present invention relates to compounds suitable as modulators of protein misfolding and/or protein aggregation. The compounds are particularly suitable as inhibitors of amyloid aggregate formation and/or modulators of amyloid surface properties, and/or as activators of degradation or reduction of amyloid aggregates.

Azaparacyclophanes with Metal-binding Sites. Part 1. Preparation, Characterization, and Molecular Recognition Behaviour of Hexapus Azaparacyclophane and its Iron(III) Complex

Hisaeda, Yoshio,Ihara, Takeshi,Ohno, Teruhisa,Murakami, Yukito,Maeda, Yonezo

, p. 595 - 604 (2007/10/02)

All the catechol moieties of a hexapus triazaparacyclophane having three catechol moieties and six hydrocarbon chains (1) undergo coordination interactions with the iron(III) ion in a 1:1 molar ratio of 1 to iron(III) above pH 6 in an aqueous medium.Two different iron(III) complexes of 1, A and B in a 1:1 molar ratio, are in the high spin iron(III) state as characterized by electronic, EPR and Moessbauer spectroscopy: A is a hexacoordinated mononulear complex with half-protonated catecholato groups, subjected to considerable structural distortion; B is ahexacoordinated mononuclear complex with complete dissociation of all the catechol protons, retaining high structural symmetry.The molecular recognition behaviour of 1 and Fe-complex A toward hydrophobic guest molecules has been investigated in aqueous HEPES and acetate buffers at 30.0 deg C and μ 0.10 mol dm-3.The hexapus cyclophane 1 recognizes organic guests through hydrophobic and electrostatic interactions; anionic and non-ionic quests, 7-hydroxy-8-phenylazonaphthalene-1,3-disulfonate (OG) and 2-hydroxy-1-(2-pyridylazo)naphthalene (PAN), respectively, are incorporated into host 1 with binding constants of the order of 105 dm3 mol-1, while a cationic guest, 2-(p-dimethylaminostyryl)-1-ethylquinolinium (QR), is not included in the host.The guest-binding behaviour of Fe-complex A toward OG and PAN is much enhanced relative to that of 1 as effected by hydrophobic, electrostatic and coordination interactions under conditions identical to those applied to 1; the binding constant for OG is nearly pH-independent in a pH range of 3-8, while that for PAN is pH-dependent because the coordination interaction with the host is subject to change by pH.

Insecticide evaporator comprising a stabilizer

-

, (2008/06/13)

Insecticide evaporator comprising at least one volatile phosphoric ester insecticide, an agent for stabilizing the said ester against decomposition by protonization and used in an amount of 0.2 to 20% based on the weight of phosphoric ester, characterized in that the stabilizing agent contains at least one compound selected from the compounds of the chemical class of 1,3-benzodioxoles and at least one diazene.

Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator

-

, (2008/06/13)

An evaporator system adapted for emitting insect killing vapors of an insecticide therefrom and comprising a liquid or solid composition enclosed therein, said insecticide consisting in at least one volatile phosphoric acid ester which is stabilized by at least one diazene compound.

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