85000-01-7Relevant academic research and scientific papers
A NEW AND EFFECTIVE ASYMMETRIC SYNTHESIS OF 3-PHENYLALKANALS
Mukaiyama, Teruaki,Hayashi, Hiroki,Miwa, Tetsuo,Narasaka, Koichi
, p. 1637 - 1640 (1982)
Highly optically active 3-phenylalkanals were obtained by the reaction of alkyl halides and a chiral homoenolate equivalent derived from the cinnamyl ether 3 and potassium diisopropylamide, followed by acidic hydrolysis.
CHIRAL HOMOENOLATE EQUIVALENTS. I. ASYMMETRIC SYNTHESIS OF β-SUBSTITUTED ALDEHIDES VIA METALATED CHIRAL ALLYLAMINES
Ahlbrecht, Hubertus,Bonnet, Gerhard,Enders, Dieter,Zimmermann, Gerd
, p. 3175 - 3178 (2007/10/02)
Metalated chiral allylamines of type 2 (M = Li, K) are used as chiral homoenolate equivalents and allow after alkylation and acidic hydrolysis asymmetric C-C bond formations to β-substituted aldehydes in enantiomeric excesses up to 67percent.
