850011-37-9

Basic information

• Product Name: 5-bromo-1-[3-(4-bromo-2-methoxyphenyl)-2-propenoyl]-3,5-dimethylpyrazole
• Synonyms: 5-bromo-1-[3-(4-bromo-2-methoxyphenyl)-2-propenoyl]-3,5-dimethylpyrazole
• CAS NO: 850011-37-9
• Molecular Weight: 414.096
• Mol File: 850011-37-9.mol

Chemical Properties

• CAS DataBase Reference: 5-bromo-1-[3-(4-bromo-2-methoxyphenyl)-2-propenoyl]-3,5-dimethylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-1-[3-(4-bromo-2-methoxyphenyl)-2-propenoyl]-3,5-dimethylpyrazole(850011-37-9)
• EPA Substance Registry System: 5-bromo-1-[3-(4-bromo-2-methoxyphenyl)-2-propenoyl]-3,5-dimethylpyrazole(850011-37-9)

Safety Data

• Hazardous Substances Data: 850011-37-9(Hazardous Substances Data)

Upstream product

• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 3398-16-1 4-Bromo-3,5-dimethylpyrazole 

Relevant articles and documents

Enantioselective enol lactone synthesis under double catalytic conditions

(Chemical Equation Presented) The reaction of dimedone with 1-(2-alkenoyl)-4-bromo-3,5-dimethylpyrazoles in THF, catalyzed by catalytic amounts of both DBFOX/Ph-nickel-(II) perchlorate trihydrate and 2,2,6,6-tetramethylpiperidine, in the presence of acetic anhydride in THF produces the corresponding enol lactones in high enantioselectivities through enantioselective Michael additions followed by cyclization with removal of the pyrazole auxiliary. Other related nucleophile precursors can be successfully applied in the enantioselective enol lactone synthesis under the double catalytic conditions.