85006-08-2

Usage

Uses

Used in Perfume and Personal Care Industry:
o-Tolyl 3-methylsalicylate is used as a fragrance ingredient for adding a sweet, fruity scent to perfumes and personal care products such as soaps, shampoos, lotions, and detergents.
Used in Food Industry:
This chemical compound is also used as a flavoring agent in food products to impart a grape-like flavor.
Used in Insecticide Industry:
Furthermore, o-tolyl 3-methylsalicylate serves as a mosquito repellent in some insecticides, providing a practical application in pest control.
It is important to handle o-tolyl 3-methylsalicylate with care and store it according to safety guidelines to ensure its safe use in the aforementioned applications.

InChI:InChI=1/C15H14O3/c1-10-6-3-4-9-13(10)18-15(17)12-8-5-7-11(2)14(12)16/h3-9,16H,1-2H3

Upstream product

• 75-44-5 phosgene 
• 95-48-7 ortho-cresol 
• 201230-82-2 carbon monoxide 

Downstream Products

• 83-40-9 3-methylsalicylic acid 
• 95-48-7 ortho-cresol 

Relevant academic research and scientific papers

Rhodium-Catalyzed Carbonylative Synthesis of Aryl Salicylates from Unactivated Phenols

A rhodium-catalyzed carbonylative transformation of unactivated phenols to aryl salicylates is described. This protocol is characterized by utilizing 1,3-rhodium migration as the key step to provide direct access to synthesize ohydroxyaryl esters. Various desired aryl o-hydroxybenzoates were produced in moderate to excellent yields with bis(dicyclohexylphosphino)ethane (DCPE) as the ligand. Interestingly, diphenyl carbonate was formed as the main product when 1,3-bis(diphenylphosphino)propane (DPPP) was used as the ligand. A plausible reaction mechanism is proposed.

Metal Template ortho-Acylation of Phenols. Direct Synthesis of Salicylic Acid Chlorides and Derivatives

A direct synthesis of salicylic acid chlorides is achieved via "metal-driven" intracomplex acylation of bromomagnesium and aluminum phenoxides with phosgene.Salicylic acids 5 and some derivatives 6, 7 can be obtained by quenching the reaction mixture with convenient reagents.Moreover the reaction of lithium phenylacetylide with 3 provides a new convenient approach to ortho-hydroxyaryl alkynyl ketones like 8.The oriented complex 2, involving the metal phenoxide and phosgene is proposed to account for the ortho-regioselective control of the reaction.