850083-29-3

Basic information

• Product Name: N-(3-aminophenyl)-2,6-difluorobenzamide
• CAS NO: 850083-29-3
• Molecular Formula: C₁₃H₁₀F₂N₂O
• Molecular Weight: 248.2281
• Mol File: 850083-29-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 321.4°C at 760 mmHg
• Flash Point: 148.2°C
• Density: 1.386g/cm³
• Vapor Pressure: 0.000298mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: N-(3-aminophenyl)-2,6-difluorobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-aminophenyl)-2,6-difluorobenzamide(850083-29-3)
• EPA Substance Registry System: N-(3-aminophenyl)-2,6-difluorobenzamide(850083-29-3)

Safety Data

• Hazardous Substances Data: 850083-29-3(Hazardous Substances Data)

Upstream product

• 18063-02-0 2,6-difluorobenzoylchloride 
• 68621-88-5 (3-aminophenyl)carbamic acid tert-butyl ester 

Relevant articles and documents

Substituted diarylurea derivative as well as preparation method and application thereof

The invention relates to a substituted diarylurea derivative as well as preparation and application thereof. Specifically, the invention discloses a compound with a formula (I) or an optical isomer, a cis-trans-isomer or a pharmaceutically acceptable salt thereof, and a preparation method thereof, wherein the definition of each substituent group in the general formula is described in the specification and claims. The invention further discloses a composition containing the compound and application of the composition. The compound disclosed by the invention has excellent anti-cancer activity on HepG2 liver cancer cells, MGC 803 gastric cancer cells, MCF 7 breast cancer cells and the like, and has a good inhibition effect on the growth of human umbilical vein endothelial cells (HUVEC).