850339-33-2

Upstream product

• 554-00-7 2,4-Dichloroaniline 
• 623-00-7 4-bromobenzenecarbonitrile 
• 70-23-5 ethyl Bromopyruvate 
• 850339-12-7 N₁-(2,4-dichlorophenyl)-4-bromo-1-benzenecarboximidamide 
• 850339-22-9 ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-hydroxy-4,5-dihydro-1H-4-imidazolecarboxylate 

Downstream Products

• 850339-39-8 2-(4-bromo-phenyl)-1-(2,4-dichloro-phenyl)-1H-imidazole-4-carboxylic acid 2-piperidin-1-yl-ethyl ester 
• 850338-96-4 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylic acid 

Relevant academic research and scientific papers

Silver-Catalyzed [3+2] Cycloaddition of Azomethine Ylides with Isocyanides for Imidazole Synthesis

A silver-catalyzed aerobic oxidative [3+2] cycloaddition of azomethine ylides with aryl or heteroaryl isocyanides has been developed. The reaction represents a novel protocol for the efficient and practical synthesis of 1,2-diarylimidazoles bearing a broad range of substituents in good to excellent yields under mild conditions. The practicability of this cycloaddition was shown by a gram-scale synthesis and a double cycloaddition for the construction of highly conjugated polyarylimidazole systems. (Figure presented.).

Synthesis, structure-activity relationships at the GABAA receptor in rat brain, and differential electrophysiological profile at the recombinant human GABAA receptor of a series of substituted 1,2-diphenylimidazoles

A series of new 1,2-diphenylimidazole derivatives (1a-x) were synthesized and evaluated for their ability to potentiate γ-aminobutyric acid (GABA)-evoked currents in Xenopus laevis oocytes expressing recombinant human GABAA receptors. Many of t