850402-76-5Relevant academic research and scientific papers
Convenient preparation of 5-alkylidene-2,5-dihydropyrrol-2-ones by ring-transformations of γ-alkylidenebutenolides: Formal synthesis of pukeleimide A
Haase, Christian,Langer, Peter
, p. 453 - 456 (2005)
The reaction of γ-alkylidenebutenolides, readily available by cyclization of 1,3-bis-silyl enol ethers with oxalyl chloride, with amines in glacial acetic acid allows a convenient synthesis of 5-alkylidene-2,5- dihydropyrrol-2-ones. This method was applie
Synthesis of 5-alkylidene-2,5-dihydropyrrol-2-ones based on cyclizations of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with oxalyl chloride
Haase, Christian,Langer, Peter
experimental part, p. 4530 - 4539 (2009/10/02)
The acid-mediated reaction of amines with γ-alkylidenebutenolides, readily available by cyclization of 1,3-bis(silyloxy)-1,3-butadienes with oxalyl chloride, allows a convenient synthesis of a variety of 5-alkylidene-2,5-dihydropyrrol-2-ones. The configur
