850424-15-6

Basic information

• Product Name: 2-Quinazolinamine, N-[3-(1,1-dimethylethyl)phenyl]-6-methoxy-
• CAS NO: 850424-15-6
• Molecular Formula: C19H21N3O
• Molecular Weight: 307.395
• Mol File: 850424-15-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Quinazolinamine, N-[3-(1,1-dimethylethyl)phenyl]-6-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Quinazolinamine, N-[3-(1,1-dimethylethyl)phenyl]-6-methoxy-(850424-15-6)
• EPA Substance Registry System: 2-Quinazolinamine, N-[3-(1,1-dimethylethyl)phenyl]-6-methoxy-(850424-15-6)

Safety Data

• Hazardous Substances Data: 850424-15-6(Hazardous Substances Data)

Upstream product

• 73428-02-1 5-methoxy-2-nitrobenzaldehyde ethylene acetal 
• 64389-34-0 5-methoxy-2-aminobenzaldehyde ethylene acetal 
• 20357-24-8 5-methoxy-2-nitro-benzaldehyde 
• 850424-10-1 6-methoxyquinazolin-2-ol 
• 850424-11-2 2-chloro-6-methoxyquinazoline 
• 5369-19-7 3-tert-butylaniline 
• 850424-09-8 ethyl (2-formyl-4-methoxyphenyl)carbamate 

Downstream Products

• 1361129-27-2 C₂₅H₂₅N₅O₂ 
• 850424-16-7 C₁₈H₁₉N₃O 

Relevant articles and documents

Design and synthesis of 6,6-fused heterocyclic amides as raf kinase inhibitors

Compounds belonging to several scaffolds-quinazolines, quinolines and quinoxalines-were designed and synthesized as Raf kinase inhibitors. Scaffolds were assessed for in vitro BrafV600E inhibition, and overall kinase selectivity. Pharmacokinetic parameters for one of the scaffolds were also determined.