850534-46-2Relevant academic research and scientific papers
Enantioselective Ir-Catalyzed Bidirectional Reductive Coupling
Quintard, Adrien,Rodriguez, Jean
supporting information, p. 453 - 456 (2019/01/23)
In the presence of a chiral iridium complex, commercially available 3-chloro-2-chloromethyl-1-propene (1) was selectively activated for various reductive couplings. Depending on the reaction conditions it allows a selective mono- or bidirectional condensa
A new construction of 2-alkoxypyrans by an acylation-reductive cyclization sequence
Heumann, Lars V.,Keck, Gary E.
, p. 1951 - 1954 (2008/02/02)
A new convergent synthetic approach to a pyran motif common to many naturally occurring structures is described. In this approach, two fragments are joined by esterification, and a subsequent intramolecular reductive cyclization affords the 2-hydroxypyran.
Enantio- and diastereoselective additions to aldehydes using the bifunctional reagent 2-(chloromethyl)-3-(tributylstannyl)propene: Application to a synthesis of the C16-C27 segment of bryostatin 1
Keck, Gary E.,Yu, Tao,McLaws, Mark D.
, p. 2543 - 2550 (2007/10/03)
(Chemical Equation Presented) Reactions of the bifunctional allylstannane 2-(chloromethyl)-3-(tributylstannyl)propene with aldehydes have been examined. These generally occur in high yields using Lewis acid promoters and the products can be isolated and p
