850559-48-7Relevant academic research and scientific papers
A new route for the convenient synthesis of 3-aminomethyl-3,5,5-trimethyl- cyclohexanol
Pandey, Satish C.,Singh, Sudhir S.,Patro, Balaram,Ghosh, Anil C.
, p. 2705 - 2707 (2007/10/03)
There has been a considerable chemical and biological interest in influenza fusion inhibitors namely, 3-aminomethyl-3,5,5-trimethyl-cyclohexanol 5. This compound has been identified as an important inhibitor of influenza virus fusion derivative and a potent and effective surrogate for the quinolizidine moiety. A new convenient route for the synthesis of 5 and for two new intermediates 1,3,3-trimethyl-5-oxo-cyclohexane-carboxylic acid amide 3 and 5-hydroxy-1,3,3-trimethyl-cyclohexane-carboxylic acid amide 4.
